LS26 Targeted Prevention / Scope of the Call

The aim of this call is to enable innovative and impactful research that has the potential to promote disease prevention and/or increase the number of healthy life years in a defined population. Projects should seek to improve a specific health condition or the prevention of a specific disease by developing targeted interventions for that population.

Key requirements

Please consider the following key requirements for all projects in this call:

• Projects must identify a specific risk population (e.g., genetic background, demographic/socioeconomic group), define a disease or health condition (e.g., cardiovascular, mental, infectious), and develop an actionable mechanism for intervention (e.g., pharmaceutical, lifestyle, social, policy-based).
• Projects must demonstrate scientific innovation (e.g., new biological mechanism, screening technology, method of engaging target population) and the value of this innovation in addressing an open research gap in prevention research.
• Projects must outline a pathway to implementation that allows for the assessment of the feasibility and impact of the proposed work (e.g., inclusion of consultations with target group, co-development frameworks, health economic considerations)
• Project teams should demonstrate scientific expertise from relevant research disciplines, as well as further expertise (e.g., on lived experience, implementation barriers, etc.) from relevant stakeholders (e.g., patient groups, advocates, practitioners, policymakers). Budget may be allocated for non-academic stakeholders as appropriate.
  

Proposals must fulfil all requirements to be considered within the scope of the call. Should any single requirement not be addressed, the proposal will be deemed out of scope and not further evaluated.

Further considerations

This call takes an inclusive approach to prevention, both with respect to the the health conditions to be addressed and the modalities of intervention. While "targeted prevention" shares thematic elements with biomedical/clinical and public health research, the focus of this call is the development of evidence-based interventions that are innovative and impactful. In addition to fulfiling all key requirements, please also consider the following:

• This call is open to research focusing on diverse aspects of health and disease, including physical, cognitive, mental, social well-being, etc.
• Research focusing on primary or secondary prevention and covering the entire lifespan is within the scope of this call.
• This call encourages research that considers various intervention modalities, including clinical, pharmaceutical, behavioural, environmental, social, and policy-based approaches.
• Research should go beyond improving understanding of the aetiology or epidemiology of diseases and encompass the development and piloting of interventions for their prevention.
• This call encourages projects that aim to develop interventions for populations that are underrepresented, marginalised or disproportionately affected by a health/disease condition. However, research focusing solely on health disparities (e.g. the social determinants of health) does not fulfil the requirements of this call.
• Projects should ensure appropriate involvement of the risk populations and relevant data from these populations. Applicants must consider ethical and legal requirements, the quality and quantity of data required for sufficiently powered studies, and the timeliness of acquiring data.
  • Based on recent experience, WWTF considers gaining access to data from health insurance companies in Austria to be extremely unreliable, even when an initial commitment to data access has been provided. Negotiations with these organisations regarding data access may exceed the project’s timeframe.
    

Outside of scope

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• The proposed projects should strongly reflect the ideas and principles of Digital Humanism and thus bring together social and technological progressfocus on a leveldefined playingpopulation field.or include ways to improve health or disease prevention for that population.
• Projects shouldfocused aimon general health literacy or attitudes towards medical research (e.g., scepticism about science), which do not focus on a defined target population or specific interventions to improve health or disease prevention for athat comprehensivepopulation.
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• Purely biomedical or preclinical research (e.g., dissection of digital technologies and practices based on insights from both ICT sciences and SSH.
• Projects may place varying emphases on methods development, theoretical and conceptual work,risk or theprotection addressing of real-world cases. However, all proposed projects should improve understanding of current fundamental questions regarding the social and human aspects of digital technologies and practices, and thus contribute to the rethinking of existing developments in digital technologies and practices.
• Applicants are especially invited to make theoretical contributionsfactors) that expanddo Digitalnot Humanism as a conceptual space within which a wider range of digital technologies and practices can be understood. The focus of the theoretical contributions may either be in the ICT fields or in the SSH fields. However, based on the call’s intention to foster interdisciplinary collaboration, both fields should be represented in developing theoretical approaches.
• Because Digital Humanism often cannot rely on an established set of methods to engage with research questions in an interdisciplinary way, applicants are encouraged to dedicate time and resourcesextend to the development of thesean methods.intervention strategy in a target population.
• Projects inthat theprimarily area of digital humanities/computational social sciences, i.e., the prevalent use of computational methodsaim to researchdevelop questionstreatments in(e.g., thecuring, SSH,controlling areor notalleviating withinsymptoms) theor scopetertiary ofprevention thisinterventions call.
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• Thereducing developmentcomplications ofor newfacilitating applicationsrehabilitation) and tools to pursue the idea of Digital Humanism is possible within the project. However, they should be regarded asonce a meansdisease tohas addressbeen fundamental research questions of Digital Humanism and thus not be the main output of the project.established.
  

Interdisciplinary Collaboration 

A central focus of this call, and of Digital Humanism in general, is to promote collaboration between ICT-related researchers and SSH. Researchers from both ICT-related fields and SSH (including art-based research) should therefore collaborate across disciplines. This should be reflected accordingly in the team composition. Both areas should contribute to the project in a substantial way, although one area may assume a larger role in the project if justified by the specific topic of the project.

Plans for collaboration between ICT and SSH areas must be demonstrated throughout all critical stages of the project, from the formulation of the research question and empirical research to the production of the project’s output. Applicants are required to explicitly address communication and joint work plans among collaborators in the proposal.