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**Abstract ***(max. 1,500 characters)* Provide an overall summary of the project. Clearly state the research questions and aims, and outline the methodological approach. Describe the research's most innovative aspects, as well as its potential impact and contribution. --- **Proposal** Background and state of the art ** ***(max. 2,000 characters)*** **Provide a broad scientific introduction to the topic of the project. Describe the state of the art, as well as current challenges and research gaps in this field. Research questions, objectives, and/or hypotheses** ***(max. 2,000 characters)*** ** Outline the research questions to be addressed in the project. Define the risk population and the health/disease condition to be targeted. Describe how the research objectives align with the development of a preventive intervention. Methodology** ***(max. 3,500 characters)* Describe the methods to be used in the project to address the research questions and to develop a preventive intervention. Provide sufficient information about the innovation, suitability and feasibility of these approaches. Outline how the project includes the relevant scientific and non-academic expertise to achieve its objectives. Pathway to implementation *(max. 2,500 characters)* Outline a structured roadmap for integrating the intervention to be developed in the project into broader practice. Depending on the scope of the proposed project, for example, this pathway may range from initial implementation, monitoring and/or evaluation of a pilot intervention to measures that facilitate its integration into standard practice. Please note that the full implementation process may extend beyond the duration of this project. While full details of the implementation process are not required, the most relevant factors should be identified and discussed (e.g. stakeholders, key steps and their timeline, required resources) to demonstrate the intervention's feasibility and impact. Contribution and impact** ***(max. 1,500 characters)* Describe how the proposed work will promote health or prevent disease in the target population, while also contributing to research in this area. Briefly explain how the data, knowledge, resources and/or technology developed during the project will be managed and shared with the research community.Please note that ****potential sex/gender aspects of the research topic** **and** **gender balance in the research team** **should be considered throughout the application (see [here](https://wiki.wwtf.at/books/ls26-targeted-prevention/page/ls26-targeted-prevention-gender-aspects-in-the-application-phase "LS25 / Gender aspects in the application phase")). These should be briefly described where appropriate in the relevant sections. Further details will be required in the full proposal phase.
--- **Project Schedule / Overview** Upload a 1-page visual representation (e.g., table, Gantt chart, flow chart) to provide an overview of the milestones to be achieved during the project. Indicate the time periods and specify the respective PIs responsible for each milestone. **Ethical considerations*** (min. 100 characters, max. 800 characters)* Outline the potential ethical aspects of your proposed project. These may include, but are not restricted to human participants, human tissue, human embryonic tissue, personal data, animals, environmental safety, and artificial intelligence. Please indicate if a formal ethical approval is necessary to conduct your research project in your institution. We advise reaching out to your institutional ethics boards prior to submitting your proposal. More detailed information regarding the ethical aspects of your proposed work and the timelines for ethical approval are required in the full proposal. Should your proposal be selected for funding, the submission of the required ethics votum for carrying out the work is a prerequisite for the funding contract. Further details about ethical requirements are available [here](https://wiki.wwtf.at/link/1215#bkmrk-ethical-aspects). If no ethical aspects are identified, please also provide an explanation. Note that only providing a cursory statement (e.g., "no ethical aspects") will not be regarded as sufficient consideration of ethical aspects by the applicants. **Use of generative AI ***(max. 800 characters)* Please describe if and how GenAI has been used in developing your research proposal. Please find further details [here](https://wiki.wwtf.at/books/archiviert-life-sciences-call-2025-precision-medicine/page/ls25-use-of-generative-ai-in-the-application-process "LS25 / Use of generative AI in the application process"). ##### References In this chapter, up to 15 key references relevant for the project can be added. Please use a format recognised in your field and apply it consistently to all references.Please note that these references should focus on the content of the proposal and is not your personal publication list. The latter should be included in the CVs of the core team members.
##### Budget The short proposal requires only an overview budget for each participating institution. All institutions added in the chapter “Personnel and Institutions” will be automatically listed in the budget table. 1. Enter the sum for personnel costs at each institution. Please consider that, in the full proposal, you will be required to enter the annual gross costs (employer and employee costs = gross costs / “Brutto-Brutto-Jahresgehalt”) of all individual researchers. If you are unsure about the annual gross costs, please consult your institutional research service. Due to projected inflation rates, the full proposal system will automatically calculate a 3.5% p.a. increase in salaries over the lifetime of the project. 2. Enter the total non-personnel costs for each institution. For details about eligible costs, please see [here](https://wiki.wwtf.at/link/1213#bkmrk-8.2.%C2%A0%C2%A0%C2%A0%C2%A0%C2%A0%C2%A0-non-perso). 3. Enter the overhead costs for each institution. Note that up to 20% overhead costs may be claimed. Please consult your institutional research service also in this regard.The system will automatically calculate sums and ratios of the budget.
- Based on the information provided, the share of the budget allocated to the regions “Vienna” and “Other” will be shown for WWTF projects and to the regions “Vienna”, “Lower Austria” and “Other” for Joint Projects. - For “regular” WWTF projects, at least 80% (i.e., ≥80%) of the requested funding must be allocated to the region “Vienna”. Up to 20% (i.e., <20%) may be allocated to other partner(s) (including partners in Lower Austria). - For Joint Projects, the budget allocated to the region “Vienna” must be ≥50%. The share of the budget allocated to the region “Lower Austria” must be between 20–50% (i.e., >20% and <50%). Maximum 20% (i.e., £ 20%) may be allocated to further partner(s) located in other regions (“Other”). - The proportions of the budget allocated to personnel and non-personnel costs are also shown. Please note that, in this call, non-personnel costs should not exceed 40% of the total budget. - The system will display an alert if the inserted amounts exceed the permitted funding distribution across regions or cost types. - Please note that changing the proposal between “WWTF Project” and “Joint Project” types will reset the budget table due to differing budget distribution requirements. **Explanation of Cost Planning** *(max. 750 characters)* Outline details about the planned allocation of resources as requested in the budget.In the case of an invitation to submit a full proposal, there should not be significant changes in the requested budget compared to the short proposal. Exceptions are permitted but require justification.