This call is open to research projects that draw upon precision medicine approaches to improve the prevention, diagnosis or treatment of a human disease.
--- ##### **Scope of the Call** Projects in this call should advance understanding of a clinically relevant research question by contributing to, or utilising, insights based on high-quality datasets from well-defined patient cohorts. Anticipated research outcomes should have clear implications for improving the prevention, diagnosis or treatment of a human disease. Projects should contribute to understanding of disease pathogenesis or treatment-relevant biological processes at a mechanistic level. Research teams must demonstrate interdisciplinarity across clinical, biological, data analysis and/or engineering research fields. ##### **Who can apply?** - Core research team of up to three principal investigators (PIs) - The coordinating PI (PI&C) must be based at a university or research institute in Vienna - Co-PIs may be based outside of Vienna (funding limited to 20% of total budget) - Co-PIs from Lower Austria may apply for up to 49% of the overall budget (Joint Project) ##### **Project Duration** 24-48 months ##### **Funding** - Call budget: € 7.5 million - Project budget: € 500,000 to € 1 million ([Joint Projects](https://wiki.wwtf.at/books/archiviert-life-sciences-call-2025-precision-medicine/page/ls25-joint-projects-with-partners-in-lower-austria "ICT25 / Joint Projects with partners in Lower Austria") up to € 1.1 million) - Personnel and non-personnel costs may be claimed - Maximum 40% non-personnel costs - Up to 20% overhead costs ##### **Timeline** - Short Proposal deadline: May 6, 2025, 2pm CET - Full Proposal deadline: October 7, 2025, 2pm CET - Applicant response phase: between February 9-20, 2026(exact dates TBD) - Expected funding decision: March 2026 - Project start: latest September 2026 ##### **Process** - Two-stage selection process - International jury - International peer review - Application via [WWTF Funding Portal](https://fundingportal.wwtf.at/) # LS25 Precision Medicine / Call Specifications This document specifies the processes, criteria, and instrument of the Life Sciences Call 2025 in Precision Medicine. It is intended for applicants wishing to submit a proposal in this project call. # LS25 / Scope of the callThis “Precision Medicine” call is issued within the WWTF Life Sciences Programme. This call is open to research projects that draw upon precision medicine approaches to improve prevention, diagnosis or treatment of a human disease.
Please consider the following **key requirements** regarding scope of projects in this call: - Projects should advance understanding of a clinically relevant research question by contributing to, or utilising, insights based on high-quality datasets from well-defined patient cohorts. - Anticipated research outcomes should have clear implications for improving the prevention, diagnosis or treatment of a human disease. - Projects should contribute to understanding of disease pathogenesis or treatment-relevant biological mechanisms. - Research teams should demonstrate interdisciplinarity across clinical, biological, data analysis and/or engineering expertise. - Consideration of the role of sex and gender in the development and treatment of diseases is essential. Within the domain of precision medicine, this call is open to projects with diverse aims and methodologies. The following research directions are considered **within the scope** of this call. Please note that this is not a comprehensive overview and that all projects must demonstrate fulfilment of the above key requirements. - Projects may aim to develop novel targeted therapies based upon understanding of disease pathogenesis and patient heterogeneity. - Projects may involve the development of novel preclinical models based on patient cohort data to improve understanding of the pathogenesis and/or treatment outcome of a human disease. - Projects may focus on understanding disease susceptibility in heterogeneous populations and seek to contribute to the development of targeted preventive interventions. - New patient datasets may be generated or assembled as part of the project, or projects may draw on existing datasets. Should new datasets be generated, demonstration of access to well-characterised cohorts and feasibility of attaining the required ethical approvals in a timely manner will be required. Please see the [requirements](https://wiki.wwtf.at/books/archiviert-life-sciences-call-2025-precision-medicine/page/ls25-guidelines-for-good-scientific-practice-and-ethics) in this call regarding ethical approvals. Please note that the following types of projects are deemed to be **outside the scope** of this call: - Public health studies that do not contribute to mechanistic understanding of a disease or therapeutic treatment. - Basic biomedical research and technology development in the absence of specific clinical rationale and implications. - Clinical trials of medicinal products. # LS25 / Structure of the CallThis call follows a two-stage selection process, consisting of a short proposal and full proposal phase.
- **Short proposals**: Applicants provide a short description of the project’s background, objectives and methodology, along with a budget overview.Short proposal deadline: May 6th, 2025, 2pm CET
- **Full proposals:** Proposals selected by the jury are invited to submit an extended proposal that includes a detailed project budget. Applicants will have the opportunity to respond in writing to the external reviews of the full proposal.Full proposal deadline: October 7th, 2025, 2pm CET
Applicant response phase: February 9th – 20th, 2026 (*Applicants invited to submit a full proposal will be notified of exact dates in late January)*
# LS25 / SubmissionApplications must be submitted via the [WWTF Funding Portal](https://fundingportal.wwtf.at/). All application information will be processed via this system.
- All core team members, i.e., coordinating PI (PI&C) and co-PIs, may access and edit the proposal. **Only the PI&C can submit the proposal.** - The structure of the proposal and steps for completing the application in the WWTF Funding Portal are described in more detail in the Submission Guideline, which will be made available in March 2025. - **Signatures of the authorized signatory at participating institutions** (“authorizations”) are required in the application process (only for institutions of core team members in the short proposal phase, also for all partner institutions in the full proposal phase). Please contact your institution’s research service in advance and inform yourself about your institute’s internal processes and timelines. - Applications must be written in **English**. # LS25 / Eligibility and roles of applicants The general eligibility of applicants is specified in the [WWTF Funding Guideline](https://wwtf.at/upload/wwtf_forderrichtlinie_08112021_final(1).pdf) *(in German only)*. A project’s **core team** may include **up to** **three Principal Investigators (PIs).** This includes a PI&C and up to two co-PIs. - Core team members may share equal management and scientific roles in the project. - The core team must have an excellent scientific track record that demonstrates the ability to conduct the proposed research project. - WWTF especially encourages young and female scientists to apply as PI. - **Each core team member must submit a CV**, which will form part of the evaluation. - A researcher may appear as a core team member (i.e., PI&C, co-PI) in a maximum of two proposals in this call. In case of three or more proposals with the same PI, WWTF will accept the first two proposals submitted. Involvement in other past / ongoing / granted WWTF projects does not impact upon eligibility to apply in this call. One PI must be designated as **PI&C** (PI and coordinator). - For legal and administrative reasons (funding contract, reporting), WWTF requires a PI&C to be named. The PI&C will be the contact person for WWTF regarding all aspects of the project. - The PI&C must have an affiliation at a Viennese research institution, which will serve as a legal contract partner. This also applies to researchers moving to Vienna, who must have a Viennese affiliation in case of funding. - The PI&C should be an expert in an area relevant to the topic of the proposal. He/she must have an excellent scientific track record and a proven capability to manage projects. Up to two **co-PIs** may also be named in the core team. - WWTF recognizes that co-PIs may have equally significant scientific roles in the project. However, the PI&C will be regarded as the main contact person for the project. - Co-PIs may be based in Vienna, Lower Austria or elsewhere (in Austria or internationally) in fulfilment of the requirements of regular WWTF projects or Joint Projects (see below). Additional **project partners and collaborators** are permitted in the research team. They can be added by name in the full proposal stage. - Non-academic collaboration partners (e.g., NGOs) may be part of the research team. How-ever, the core team members and majority of additional team members in the proposal should have an academic background. - Industry partners are not eligible for funding, but may partake with in-kind or financial contribution. **Research partners outside Vienna: ** - For regular WWTF projects, project partners outside of Vienna may receive up to 20% (i.e., <20%) the total requested funding. - This call operates under the [“Joint Projects” agreement with the Province of Lower Austria](https://wiki.wwtf.at/books/archiviert-life-sciences-call-2025-precision-medicine/page/ls25-joint-projects-with-partners-in-lower-austria "ICT25 / Specifics of Joint Projects with partners in Lower Austria"). # LS25 / Joint Projects with partners in Lower AustriaWWTF welcomes **Joint Project (JP) applications** between Viennese and Lower Austrian universities and research institutions in this call.
The aims of this initiative are to promote research cooperation between Lower Austria and Vienna on equal terms and to strengthen cooperation of research institutions in the Vienna region. - To incentivize the cooperation, the total maximum funding amount for a JP consortium is € 1.1 million (i.e., an additional € 100,000 compared to the maximum for a regular WWTF project). - The PI&C must be affiliated to a research institution in Vienna. - At least one co-PI must be affiliated to a research institution in Lower Austria. - The share of the overall funding allocated to research institutions in Lower Austria must be >20% and <50%. In case that the Lower Austrian share is ≤20%, the project is considered as a regular WWTF project and is not eligible for the higher maximum funding amount. - The Lower Austrian share is financed by the Province of Lower Austria. Hence, the Lower Austrian project partner must comply with the [Lower Austrian Culture ](http://www.noe.gv.at/noe/Kunst-Kultur/Richtlinien_zum_Noe_Kulturfoerderungsgesetz_1996_3.pdf)[Promotion Act 1996 and the directives](https://www.noe.gv.at/noe/Wissenschaft-Forschung/Richtlinien_zum_Noe_Kulturfoerderungsgesetz_1996_2.pdf) issued on the basis thereof. Further details will be provided in the funding contract. - Partners outside Vienna or Lower Austria are also possible and may request up to 20% (i.e., <20%) of the total budget. However, the share of the budget allocated to partner(s) in Vienna must be at least 50% (i.e., ≥50%). - Regional branches of Viennese Institutions (e.g., BOKU, VetMed, AIT) located in Lower Austria are considered as Vienna-based in the context of WWTF funding activities.A conversion between JPs and regular WWTF projects is not possible between the short and full proposal phases.
| **Short Proposal ** | **Full proposal ** |
| Scientific abstract | Lay summary and scientific abstract |
| Project description (about 3 pages): outline of the main scientific research idea and approach | Project description (about 12-15 pages): elaboration on the research idea and approach (template is provided) |
| Project core team: CVs and roles in project (mandatory template is provided) | Project team and further collaboration partners: CVs for all core team members (mandatory template is provided) and roles in project of all team members |
| Budget overview | Detailed budget |
| Brief statement regarding ethical aspects | Ethical approval OR detailed description of ethical aspects, including feasibility and timeline for ethical approval |
| Signatures: from the authorising persons at the institutions of the core team members | Signatures: from the authorising persons at all participating institutions |
Please note that the short proposal is intended for a jury panel with expertise covering a range of proposals, while the full proposal is primarily aimed at experts in the specific topics of the proposal.
# LS25 / Evaluation criteria The following criteria are used in the evaluation. - **Scope**: Is the project within the [scope](https://wiki.wwtf.at/books/archiviert-life-sciences-call-2025-precision-medicine/page/ls25-scope-of-the-call "LS25 / Scope of the call") of the call?Projects that do not meet the key requirements regarding scope will be rejected by the jury, regardless of scientific quality.
The key criteria in the evaluation of proposals are **scientific excellence of the project and applicants**, and the r**elevance and impact** of the proposed research: - **Scientific innovation of the proposed research project**: What is the scientific novelty and transformative potential of the proposed approach? Does the proposed research work meet the highest relevant international standards? - **Relevance and impact**: How does the proposed work address unmet clinical needs? To what extent does the project have potential to advance prevention, diagnosis or treatment for patients? What are the mid- to long-term academic and clinical impacts of the advancements expected from the project? - **Scientific excellence and academic potential of the applicant(s)**: Do the applicants demonstrate the expertise and potential to conduct the proposed research? Please note that scientific track record is measured according to academic age. Further criteria: - **Feasibility:** Are the timeframe and budget adequate for carrying out the project? Are the proposed resources suitable for achieving the goals? Overall, how likely is the project to contribute to advances in precision medicine? - **Team composition and interdisciplinary collaboration: **Teams should include an appropriate mix of expertise, bringing together researchers from complementary scientific disciplines if required. A clear description of the roles of the individual partners and a clear project management plan must be presented. - **Data management:** How will research data be managed and shared? Has the sustainability and impact of new resources been considered? Please also consider [WWTF’s Open Science Policy](https://wiki.wwtf.at/books/archiviert-life-sciences-call-2025-precision-medicine/page/ls25-open-science "ICT25 / Open Science"). - **Consideration of gender aspects**: The relevance of potential sex-specific and gender-related aspects of the proposed projects should be considered and explained throughout the proposal. Please consider [WWTF's guidelines regarding sex and gender in research](https://wiki.wwtf.at/books/archiviert-life-sciences-call-2025-precision-medicine/page/ls25-gender-aspects-in-the-application-phase "ICT25 / Gender aspects in the application phase"). Other aspects: - **Career breaks** such as for parental leave, care duties and longer illnesses will be taken into account in the evaluation of the proposals. Please indicate the time periods in the applicants' CV to allow them to be considered.Please note that the short proposal will be evaluated by a jury panel, who will be asked to act as generalists when evaluating proposals. In contrast, the full proposal will additionally be evaluated by reviewers with specific expertise in the topics of the proposal. Thus, an appropriate level of scientific detail should be provided at each stage to allow evaluation of the proposal by the respective audience.
# LS25 / Eligible costsAll costs that are directly attributable to the project and are regarded as commonly required in the respective scientific fields are eligible for funding. Please also consider your organization’s internal guidelines for eligible expenses/costs.
#### Personnel costs WWTF is dedicated to funding researchers. Hence, the larger share of the project’s budget should be allocated to personnel costs for researchers working on the project. - Eligible forms of employment contracts are full-time and part-time contracts as well as marginal employments (“Arbeitsvertrag”). Contracts for services (“Werkvertrag”) are only permitted if the nature of the work means that it cannot be performed through employment contracts. - All persons employed through a WWTF-funded project should receive a fair employment contract with at least a minimum wage according to the “Kollektivvertrag” (collective agreement) of the Austrian Universities / non-university research institutions. For staff employed at institutions without a collective agreement, the minimum wage should adhere to the standards of the Austrian Science Fund ([FWF salary scheme](https://www.fwf.ac.at/en/funding/steps-to-your-fwf-project/further-information/personnel-costs)). - Salaries higher than those stipulated in the collective agreement are possible, subject to the agreement from the host institution and justification based on qualifications of the researcher. - Due to projected inflation rates, the budget calculation for salaries in the Funding Portal automatically includes an increase of 3.5% p.a. for the duration of the project (Full proposal budget only). - Applications for personnel costs must be in one of the following categories: - **Senior Personnel: **highly qualified scientists, usually permanently employed - **Post Doc: **or equivalent qualification, including Senior Postdocs - **PhD Student: **or equivalent qualification level - **Diploma Student:** Bachelor or Master students - **Office/Technician: **administrative or technicians (proportional funding only) - Personnel costs **cannot** be claimed for permanent senior staff who are already fully financed by the institution. Exceptions apply in cases where senior staff must acquire third party funding for co-financing their own position (e.g., non-university research institutions and Universities of Applied Sciences). In these cases, permanently employed senior staff may claim up to 20% of their annual salary from WWTF. #### Non-personnel costs Running costs for basic infrastructure (telephone costs, rents) as well as costs for the acquisition of infrastructure and basic equipment are **not** eligible for funding, as these should be covered by the category “overhead costs”. The following categories of non-personnel costs are eligible for funding: - **Equipment: ** Smaller equipment can be purchased with funds from the grant. This includes devices up to € 1,500 each, as well as software specific to the projects.** **General office software is not eligible for funding. Funding by WWTF in project calls is not intended to cover investment in general and larger infrastructure. However, pro rata depreciation rates over the project duration for equipment necessary to the project may be funded. - **Consumables**: Costs for project-related expenses like consumables are permitted. WWTF does not fund consumables that are general and not project-specific (e.g., paper, printer toner). - **Travel costs**: Costs for travel and accommodation for scientific meetings and conferences, field work, expeditions may be funded. Please also consider the regulations of your organization for travel costs. - **Publication costs: **Costs incurred for publication activities, e.g., printing costs, article processing charges (for open science), etc. are allowed. This also includes costs for archiving research data in open repositories. Please also consider [WWTF's Open Science Policy](https://wwtf.at/upload/wwtf_open-science-policy_09032022.pdf). - **Workshop/conferences**: Costs for organizing events, workshops, and conferences as well as for hosting invited speakers are eligible.Other costs: Third-party costs, namely, for external collaboration, consulting, studies, and software development may be funded to a limited extent. In general, individuals should be predominantly funded through employment contracts at the participating institutions and not through other types of employment. Under special conditions, costs for childcare and/or career coaching for female WWTF-funded personnel may be requested to a small degree.Non-personnel costs should not exceed 40% of the overall budget.
#### Indirect costs (overheads)WWTF pays a maximum of 20% overhead.
Overhead is calculated as a percentage of the direct costs of the project (i.e., personnel + non-personnel costs). Please note that WWTF offers the maximum 20% overhead lump sum to compensate for all administration costs. This means that flat fees for payroll or project accounting are not eligible. The total funding volume is calculated as direct plus indirect costs. Applicants are required to comply with the overhead regulations of the involved institutions. # LS25 / Gender aspects in the application phase WWTF’s [Gender Strategy and Gender Equality Plan ](https://www.wwtf.at/upload/wwtf-gender-equality-strategy-and-plan_final.pdf)must be considered throughout the application. Please note that WWTF requests jury members and reviewers to take into account both gender and specific roles in research team composition, as well as gender in research content during evaluation processes. The following questions should be considered during development of the proposal: **Equal opportunities in research** - Please take into consideration gender balance/equality in the project consortium at all levels, including in decision-making positions, e.g., what steps have been taken to approach / achieve it? - Do working conditions allow all members of staff to combine work and family life in a satisfactory manner? - Are there mechanisms in place to manage and monitor gender equality aspects, e.g., workforce statistics? **Gender in research content and in the research ideas phase** - If the research involves humans as research objects, has the relevance of gender to the research topic been analysed? - If the research does not directly involve humans, have potentially differentiated relations of men and women to the research subject (e.g., relevance, impact of findings) been sufficiently considered? - Have literature and other sources relating to gender differences in the research field been consulted? **Proposal phase** - Does the methodology ensure that (possible) gender differences will be investigated: that sex/ gender differentiated data will be collected and analysed throughout the research cycle and will be part of the final publication? - Does the proposal explicitly and comprehensively explain how gender issues will be handled? - If there are no identifiable gender aspects after a detailed review by the applicants, this must be justified, e.g., by providing reasons to demonstrate that no sex, gender, and other relevant differences have been found. **Research phase** - If there are further aspects of the project in which sex/gender could be a factor (e.g., samples, testing groups), are these gender-balanced? - Are questionnaires, surveys, focus groups, etc. designed to unravel potentially relevant sex and/or gender differences in your data? - Is data analysed according to the sex variable? Are other relevant variables analysed with respect to sex? --- **Further resources** - Gender in Research Toolkit by Yellow Window: [https://www.yellowwindow.com/genderinresearch](https://www.yellowwindow.com/genderinresearch) - Gendered Innovations, Stanford University: [http://genderedinnovations.stanford.edu/methods-sex-and-gender-analysis.html](http://genderedinnovations.stanford.edu/methods-sex-and-gender-analysis.html) - Canadian Institutes of Health Research: [https://www.cihr-irsc-igh-isfh.ca/](https://www.cihr-irsc-igh-isfh.ca/) # LS25 / Guidelines for good scientific practice and ethics #### Good scientific practice Compliance with the **rules for good scientific practice,** including the observance of ethical aspects in research, is mandatory. This pertains to the application process and, in case of funding, the research work. - WWTF is member of the Austrian Agency for Research Integrity (OeAWI) and thus committed to their standards for good scientific practice. Hence, applicants must comply to [OeAWI standards](https://oeawi.at/en/guidelines/) - In case of suspected scientific misconduct, WWTF will employ the ombudsperson at the applicant’s institution or request OeAWI to investigate the case. - Based on the outcome of investigations by the ombudsperson or OeAWI, WWTF reserves the right to exclude the applicants and the application from the involved and future calls. #### Ethical aspects Project proposals may include **ethical aspects** that require the approval from an ethics committee/institutional review board. Please consider WWTF’s requirements regarding ethical aspects at the different stages of the call and, if applicable, upon the selection of a project for funding. - In the short proposal, applicants provide a brief statement regarding the ethical aspects of the project. Applicants must indicate whether a formal ethical approval is required for the proposed work. - Upon invitation to submit a full proposal, applicants must provide a more detailed description of the ethical aspects of the proposed work. If available, the ethical approval (final or preliminary) or confirmation of submission of an ethical approval should be submitted. If an ethical approval for the proposed work has yet not been granted, applicants must provide a timeline and an explanation of the feasibility of obtaining the necessary ethical approvals. In the latter case, applicants commit themselves to obtaining the required permits to commence the project in a timely manner, should it be selected for funding. - Upon selection for funding, submission of the final ethical approvals to WWTF is a prerequisite for the funding contract. As projects must start no later than 6 months after funding approval, grantees must ensure that ethical approvals are submitted to WWTF in time for the funding contract to be concluded.Please note that the feasibility of obtaining the required ethical approval will be considered during the evaluation of the full proposal. Insufficient demonstration of the ability to obtain ethical approvals within a timely manner may result in the project being excluded by the jury panel.
Please note the following requirements regarding **ethical approvals** for WWTF-funded projects. - The approval by the ethics committee should be specific for the planned WWTF project. Therefore, the title of the project should be the same as on the approval (minor deviations are possible). If the title of the approved research differs significantly from the proposed project, a statement must be provided (in the Funding Portal), confirming that the approval will cover the planned research. - If the main applicant for the ethical approval is not a core team member (i.e., PI&C or co-PI) of the WWTF proposal, a clear statement must be included in the proposal, in which a core team member confirms that he/she is authorized to conduct the planned research within this ethical approval. - If the planned research is covered by an existing approval, the applicants must submit the extension of the approval (“Verlängerung der Gültigkeit des Votums”). The above also applies for extensions.Non-compliance will result in the rejection of the proposal on formal grounds.
“Substantial use” is defined in line with the European Commission’s definition: “\[…\] using generative AI as a basic author support tool is not a substantial use. However, interpreting data analysis, carrying out a literature review, identifying research gaps, formulating research aims, developing hypotheses, etc. could have a substantial impact.” (EC 2024: Living Guidelines on the responsible use of generative AI in research.)
This mainly concerns critical parts of scientific relevance, such as hypothesis formulation and the scientific project plan. Applicants will be required to provide statements on the use of generative AIs at both the short and full proposal stages. WWTF emphasizes the importance of human responsibility for the content submitted at all stages of the application process.WWTF does not allow the use of genAI in the evaluation process.
# LS25 / Selection and decision process Applications must be submitted via the online Funding Portal in the specified timeframes. Submissions after the deadline will not be considered. The core element of WWTF’s decision-making processes is an **international jury** mandated to make a funding recommendation to the WWTF boards. - Depending on the call (size, scope etc) the jury is comprised of 6-12 outstanding international experts who have no current affiliation to an Austrian institution. - Jury members are selected by WWTF according to their expertise in the call topic. They have no known conflict of interest prior to the submission deadline. For details, see section on evaluation below. - The names of jury members will be published on the WWTF website after the WWTF Board of Directors finalize the formal funding decision. #### Formal eligibility check by WWTF WWTF office will conduct a formal eligibility check of the proposal based on the criteria outlined in the [WWTF Funding Guideline](https://wwtf.at/upload/wwtf_forderrichtlinie_08112021_final(1).pdf), and this document. This includes: - All required signatures from the appropriate persons are uploaded. - All projects will be checked for plagiarism with software. - Submission of the same or highly similar research ideas to other funding organizations, which must be explicitly declared in the full proposal. Application for funding at other organizations is permitted and will not impact the evaluation. In case of funding, applicants will be asked by which organization they wish to be funded, as double funding is not permitted by WWTF. Substantial deficiencies and missing sections in the application will lead to the exclusion of the application from further evaluation and rejection on formal grounds. The strict timeline of the call does not allow for proposals to be sent back to the applicants for amendments. #### Evaluation of short proposals - Each proposal is independently assessed by at least two jury members based on the evaluation criteria. - The jury decides in a meeting (on-site or online) if a short proposal should be invited to the full proposal stage. This usually takes place 1-2 months after the short proposal submission deadline. - All applicants will be promptly informed about the decision. Unsuccessful applicants will be provided with a short jury statement explaining the decision. Successful applicants will be informed that they are invited to submit a full-length proposal. #### Evaluation of full proposals - All duly submitted full proposals are checked again for formal aspects. Proposals which do not meet the formal requirements will be rejected at this stage. - The information provided in the full proposal must be consistent with the short proposal and extend it by providing more information and details. Major deviations to the short proposal must be justified explicitly. If major deviations cannot be satisfactorily explained, it may be rejected by the jury at this stage. Eligible full proposals will undergo a **review process**. - WWTF will obtain a minimum of two (usually 3-4) written reviews for each proposal. - Reviewers are international experts in the topic(s) of the proposals. WWTF does not contact reviewers based in Austria. WWTF aims for diversity in the cohort of reviewers for a call (gender, age, countries). - All reviewers will be checked by the WWTF office for potential conflicts of interests with the applicants. As a rule, reviewers should not have close professional relations to any of the applicants in the project team. Practically, this excludes reviewers that have published with the applicants within the last five years or have had a collaboration in a research project in this timeframe. In case of very close cooperation with the applicant(s) over a longer period of time, the reviewer will also be excluded. Joint publications in an edited volumes/proceeding, “community papers” with more than 30 authors or common attendances in workshops and conferences do not qualify as conflict of interest. Additionally, reviewers are asked to disclose any potential conflict of interest. - Reviewers will be asked to provide their assessment of the proposal through a standardised online questionnaire. - The expert reviewers remain anonymous to the applicants. - Jury members nominate reviewers. In addition, in the full proposal submissions, applicants are asked to suggest 5 experts whom they deem qualified to review the proposal. WWTF office will check the reviewers for potential conflict of interests. WWTF office is free to choose/not to choose any of the suggested experts. - Applicants may also exclude up to 3 persons without stating any reasons. Reviewers on the negative list will not be contacted. Applicants will have the opportunity to **respond** in writing to the external reviews. - The purpose of the applicant response step is to allow correction of any factual errors or conceptual misunderstandings in the external reviews. - The length of the applicant response will be limited to the equivalent of one A4 page of text. The response must be entered as text in the Funding Portal. Pictures, graphs, or other documents cannot be inserted or attached. - Applicants will be given 7 calendar days to view and respond to the peer reviews. While the exact dates for the applicant response step are not fixed, an [indicative time period](https://wiki.wwtf.at/books/archiviert-life-sciences-call-2025-precision-medicine/page/ls25-structure-of-the-call "LS25 / Struture of the Call") is provided. - All core team members will receive an email notification when the applicant response step is open in the Funding Portal. - Submission of a response to reviews is not compulsory. However, the jury panel will be informed that all teams were provided with the opportunity to respond to reviews. - More details about the scope and process of the applicant response phase will be available to core teams invited to submit a full proposal. #### Full Proposal Jury meeting The jury will convene about 3-4 months after the submission deadline of the full proposals to select full proposals to recommend for funding. The jury may be extended by additional members in case supplementary expertise is needed to cover the topics of the proposals. At least two jury members are assigned to each proposal and act as rapporteurs for the proposals. - The basis for the evaluation by the jury are the full proposals, the external reviews, and the applicant’s response to reviews. The arguments brought forward in the review reports will be carefully balanced with the jury’s own expertise. - The result is a recommendation for each project: “to be funded” or “not to be funded”. #### Formal funding decision The jury recommendation will be formally confirmed first by the WWTF Advisory Board and then approved by the WWTF Board of Directors. - Applicants will be promptly informed about the decision. - The decision may include budget cuts as well as additional conditions and recommendations. - Unsuccessful applicants will receive a short statement by the jury explaining the main reasons why the project was not selected for funding.Please note that WWTF does not allow the opportunity for rebuttals to either recommendations by the jury panel or decisions by the WWTF Board of Directors.
# LS25 / Funding contract In case of funding, WWTF office will contact the PI&C to draw up the funding contract. - WWTF encourages projects to start as soon as possible after the formal funding decision by the WWTF Board of Directors. To facilitate a timely project start, WWTF will directly contact the PI&C shortly after the funding decision to commence the contracting process. - The formal start of the project may be **no later than 6 months** after the formal funding decision. Please note that WWTF does not require all team members of the funded project to begin by the project’s start date. However, WWTF expects grantees to nominate a formal starting date for their project that is no later than 6 months after the notification of the funding decision. - The PI&C will be provided with the necessary documents for the contracts. - The formal funding contract will be signed between WWTF and the host institution of the PI&C. In Joint Projects, the host institution of the co-PI in Lower Austria is an additional contract partner. - For universities, this is a project according to §27 of the Universities Act 2002. The institution then authorizes the respective PI to sign for the full scientific and financial responsibility of the project. # LS25 / Monitoring and reporting Funded teams commit themselves to delivering reports and participating in evaluation and monitoring. WWTF offers the possibility to adapt the work plan according to project needs. For details, see the [Reporting and Accounting Guideline](https://wwtf.at/upload/anhang_berichtswesen-und-abrechnungsmodalitaten_17072024.pdf). # LS25 / Community Building WWTF is highly committed to supporting the growing ICT community in Vienna. To this end, several community building activities will be offered throughout the funding cycle. Funded teams will be invited to participate in these activities to foster collaborations between and beyond WWTF funded projects. # LS25 Precision Medicine / Short Proposal / Submission Guideline This section is a guide to using WWTF’s Funding Portal. It is intended for applicants who wish to submit a short proposal in the Life Sciences Call 2025. # LS25 / Short Proposal / Register & LoginAll proposals must be submitted electronically via the WWTF’s Funding Portal.
##### **Registeration** 1. Go to [https://fundingportal.wwtf.at/](https://fundingportal.wwtf.at/) 2. Go to “Register” in the top menu 3. Enter your registration data (\*indicates mandatory fields) 4. You will receive an email to confirm registrationIf you are a PI, please register and complete your profile as early as possible because your profile information is used in the other parts of the proposals (e.g., your institution).
Please note that the person who initially registers must not necessarily be the PI&C of the project. The PI&C and co-PIs can be invited to the proposal at a later time.Administrative staff (e.g., institutional grants office, project assistants) can also create a proposal and invite PIs. Only in this case can a proposal be edited by both PIs and administrative staff (i.e., administrative staff cannot be invited to an existing proposal). This allows research support and admin personnel to first check the requirements for submitting a proposal.
##### **Login** 1. Go to [https://fundingportal.wwtf.at/](https://fundingportal.wwtf.at/) 2. Login with your credentials # LS25 / Short Proposal / Creating a new proposalThe Funding Portal will save your entries and changes automatically. You can pause data entry at any time. All information will be available again upon your next login.
1. Go to “Calls” in the top menu 2. Under “Running calls”, select the “Life Sciences 2025 – Precision Medicine” call 3. Click “Create new proposal”. 4. Once created, you will find all your proposals under “My Proposals & Roles” in the top menu.You can create multiple proposals. However, please note that each researcher may participate as PI&C or co-PI in a maximum of two proposals. You can also delete proposals at any time. Proposals that are not submitted will be deleted automatically after the submission deadline.
# LS25 / Short Proposal / Information about PIsIn the short proposal, WWTF requires information only about the researchers in the project’s core team (i.e., the PI&C and up to two co-PIs). Further researchers beyond the core team may also take part in the project, either funded by WWTF or with in-kind contribution. Information about these further researchers will be required in the full proposal.
##### **Step 1: Invite the PI&C and co-PIs** 1. Go to the tab “Personnel and Institutions” in the proposal 2. Invite a “Principal Investigator and Coordinator” by providing their contact information. - - **In case you are the PI&C****,** please click “I am the Principal Investigator”. You can then invite further co-PIs to this proposal. - **In case you are not the PI&C****,** you will need to invite them to the proposal. The invited PI will receive an email to accept the invitation. The invited person can login with an existing account or register as a new user. You and the PI&C can then invite further co-PIs to the proposal. ##### **Step 2: Complete your “Profile”** The PI&C and all co-PIs must complete “My Profile”.** **If you are creating a project on behalf of others and are not part of the Core Team, you do not need to provide this information. 1. Go to “My Profile” in the top menu to fill out or update your profile. This information needs to be entered only once and can then be used for multiple proposals or in future calls. - - Please upload or update your [CV ](https://wiki.wwtf.at/books/archiviert-life-sciences-call-2025-precision-medicine/page/ls25-short-proposal-cv-and-list-of-publications "LS25 / CV and List of Publications")based on the template "wwtf\_cvtemplate\_project.docx". - Should you have multiple affiliations, these can be added in your profile. Different affiliations may then be used for different proposals. ##### **Step 3: Complete your “Role”** 1. Go to “My Proposal & Roles” in the top menu. Under “My Roles”, click on your role below the title of the proposal. 2. Update the personal information by clicking on “Refresh from profile”. The system will check if there is new information in “My Profile” and update this section accordingly. 3. Enter data in the respective fields: - - - Scientific expertise (*key words*) - Specific competencies for the project *(500 characters)* - Role and responsibilities within the project *(500 characters)*Please note that the information entered here should be specific to the project. If you are participating in multiple proposals that requires different subsets of your expertise, please tailor the information according to the project.
1. Select the affiliation with which you want to apply for the proposal. Please note that an authorization signature will be required from this institute for the proposal. 2. Check the box under “Affirmation” to confirm acknowledgement of and compliance with guidelines from WWTF and additional relevant organisations.As the Funding Portal automatically relays entered information about the PI&C and co-PIs into subsequent parts of the proposal, we recommend that the core team members fill out these sections early (e.g., institutions of the core team members are automatically added to the budget).
# LS25 / Short Proposal / CV and List of PublicationsThe CV template provided in the Funding Portal must be used. Please use the following template:"**All other calls: wwtf\_cvtemplate\_project.docx"**
- List all items in reverse chronological order. - For each of the selected publications (max. 10), provide 1-2 sentences outlining the relevance of the publication for the proposal. - If possible, please also provide a link to a more detailed list of your publications. This may be your institutional website, personal website, an ORCID profile, Google Scholar profile, etc. - Describe additional qualifications or skills that are relevant for the success of the project. These may extend beyond scientific skills to experience in leadership, supervision, Open Science, etc.Do not exceed 2 pages for the CV, as the system will not accept the upload of documents longer than 2 pages
##### **Different CVs in case of the submission of two proposals**Applicants have the possibility to submit two proposals. This may necessitate slightly different versions of the CV (e.g., publications specific to the proposals).
In case you wish to provide two different CVs for two proposal, the following procedure is recommended: - Under "My Profile", upload the CV for Proposal A - Go to "My Proposals and Roles" - In the section "My roles", click on "Principal Investigator and Coordinator" of Proposal A - In the page that opens, click on the green button "Refresh from Profile" This imports the CV from your profile to Proposal A, and only to Proposal A. - Go back to "My Profile" and delete the existing CV. - Upload the new CV for Proposal B - Go to "My Proposals and Roles" - In the section "My roles", click on "Principal Investigator and Coordinator" of Proposal B - In the page that opens, click on the green button "Refresh from Profile" Proposal A and B should have now have different CVs. # LS25 / Short Proposal / Overview of chapters The proposal is comprised of six chapters, each under a separated tab: - [Basic Information](https://wiki.wwtf.at/link/842#bkmrk-basic-information "LS25 / Details of chapters") - [Personnel and Institutions](https://wiki.wwtf.at/link/842#bkmrk-personnel-and-instit) - [Project](https://wiki.wwtf.at/link/842#bkmrk-project) - [References](https://wiki.wwtf.at/link/842#bkmrk-references) - [Budget](https://wiki.wwtf.at/link/842#bkmrk-budget) - [Signatures](https://wiki.wwtf.at/books/archiviert-life-sciences-call-2025-precision-medicine/page/ls25-short-proposal-signatures) A chapter with a red alert symbol indicates that it is incomplete. Within the marked chapter, click on the red symbol(s) beside individual sections to highlight the fields requiring attention. A green checkmark symbol indicates that the information in the chapter is complete.Please note that the symbols might not refresh immediately even if the information in the chapter is complete. Changing to another chapter and going back to the other will refresh the symbol.
# LS25 / Short Proposal / Details of chapters Please note that the inclusion of figures and tables is not possible in the short proposal. These elements can be included in the full proposal phase. ##### Basic Information This chapter contains basic information about the proposal, including title, scientific disciplines involved, keywords, duration, and type of project (i.e., regular WWTF Project or Joint Project). Fill out fields as required. Please note: - Scientific Disciplines: Fields will be suggested as you type. WWTF uses the [ÖFOS classification system of Statistik Austria](https://data.statistik.gv.at/web/meta.jsp?dataset=OGDEXT_KLASSDB_OEFOS2012_1). - Joint Project: Please indicate if this proposal is a Joint Project, i.e. includes partners from Lower Austria with a higher share possible from the overall project budget. For details regarding team composition and budget distribution, please see [here](https://wiki.wwtf.at/books/archiviert-life-sciences-call-2025-precision-medicine/page/ls25-joint-projects-with-partners-in-lower-austria). ##### Personnel and Institutions This chapter contains information about the main parties in the project. Ideally, [information about the PI&C and co-PIs ](https://wiki.wwtf.at/books/archiviert-life-sciences-call-2025-precision-medicine/page/ls25-short-proposal-information-about-pis "LS25 / Information about PIs")have already been entered. However, this information can be changed at any time. - **Co-PIs** can be added to the project. Please note the maximum of three PIs in the core team. - **Additional partner institutions** beyond those of the core team members can be added under “Further Partner Institutions”. (The institutions of the PI&C and co-PIs are automatically added by the system.) Entering an additional institution provides the option of allocating budget to this institution in the “Budget” chapter. This may be important in case of collaboration with researchers at institutes other than those of the core team members - A maximum of **five different institutions** may be involved in the proposal. This includes the institutions of the PI&C and co-PI(s). ##### Project This chapter contains the bulk of the scientific information regarding the project.Please note that the character limit includes spaces
**Abstract ***(max. 1,500 characters)* Provide an overall summary of the project. Clearly state the research questions and aims of the team. Summarise the most innovative aspects of the research, and its potential impact and contribution. --- **Proposal** Introduction, background and state of the art** ***(max. 2,000 characters)*** **Provide a broad scientific introduction to the topic of the project. Describe the state of the art in this research field. Research questions, objectives, and/or hypotheses** ***(max. 2,000 characters)*** ** Specify the research question(s) to be addressed in the context of the state of the art. Outline how the research objectives align with precision medicine approaches. Methodology** ***(max. 3,500 characters)* Describe the methods to be used to address the research questions. Provide sufficient information about the innovation, interdisciplinarity, suitability and feasibility of these approaches with respect to the project’s objectives. Specify how the proposed work contributes to, or utilises, patient cohort datasets. Scientific impact and contribution *(max. 2,500 characters)* Outline the project’s anticipated contribution to precision medicine. Describe how the proposed work will advance the prevention, diagnosis or treatment of a disease. Specify how the project aims to contribute to understanding of disease pathogenesis or treatment-relevant biological mechanisms. Briefly explain how the data, resources and/or technology developed in the project will be managed and shared with the research community. Interdisciplinary collaboration** ***(max. 1,000 characters)* Describe how the project team brings the necessary interdisciplinary expertise to pursue the proposed research. Outline the plans for collaboration, communication and, if applicable, training across expertise fields. **Project Schedule / Overview** Upload a 1-page visual representation (e.g., table, Gantt chart, flow chart) to provide an overview of the milestones to be achieved during the project. Indicate the time periods and specify the respective PIs responsible for each milestone.Please note that ****potential sex/gender aspects of the research topic** **and** **gender balance in the research team** **should be considered throughout the application (see [here](https://wiki.wwtf.at/books/archiviert-life-sciences-call-2025-precision-medicine/page/ls25-gender-aspects-in-the-application-phase "LS25 / Gender aspects in the application phase")). These should be briefly described where appropriate in the relevant sections. Further details will be required in the full proposal phase.
--- **Ethical considerations*** (min. 100 characters, max. 800 characters)* Outline the potential ethical aspects of your proposed project. These may include, but are not restricted to human participants, human tissue, human embryonic tissue, personal data, animals, environmental safety, and artificial intelligence. Please indicate if a formal ethical approval is necessary to conduct your research project in your institution. We advise reaching out to your institutional ethics boards prior to submitting your proposal. More detailed information regarding the ethical aspects of your proposed work and the timelines for ethical approval are required in the full proposal. Should your proposal be selected for funding, the submission of the required ethics votum for carrying out the work is a prerequisite for the funding contract. Further details about ethical requirements are available [here](https://wiki.wwtf.at/books/archiviert-life-sciences-call-2025-precision-medicine/page/ls25-guidelines-for-good-scientific-practice-and-ethics "LS25 / Guidelines for good scientific practice and ethics"). If no ethical aspects are identified, please also provide an explanation. Note that only providing a cursory statement (e.g., "no ethical aspects") will not be regarded as sufficient consideration of ethical aspects by the applicants. **Use of generative AI ***(max. 800 characters)* Please describe if and how GenAI has been used in developing your research proposal. Please find further details [here](https://wiki.wwtf.at/books/archiviert-life-sciences-call-2025-precision-medicine/page/ls25-use-of-generative-ai-in-the-application-process "LS25 / Use of generative AI in the application process"). ##### References In this chapter, up to 15 key references relevant for the project can be added. Please use a continuous reference style.Please note that these references should focus on the content of the proposal and is not your personal publication list. The latter should be included in the CVs of the core team members.
##### Budget The short proposal requires only an overview budget for each participating institution. All institutions added in the chapter “Personnel and Institutions” will be automatically listed in the budget table. 1. Enter the sum for personnel costs at each institution. Please consider that, in the full proposal, you will be required to enter the annual gross costs (employer and employee costs = gross costs / “Brutto-Brutto-Jahresgehalt”) of all individual researchers. If you are unsure about the annual gross costs, please consult your institutional research service. Due to projected inflation rates, the full proposal system will automatically calculate a 3.5% p.a. increase in salaries over the lifetime of the project. 2. Enter the total non-personnel costs for each institution. For details about eligible costs, please see [here](https://wiki.wwtf.at/link/775#bkmrk-8.2.%C2%A0%C2%A0%C2%A0%C2%A0%C2%A0%C2%A0-non-perso). 3. Enter the overhead costs for each institution. Note that up to 20% overhead costs may be claimed. Please consult your institutional research service also in this regard.The system will automatically calculate sums and ratios of the budget.
- Based on the information provided, the share of the budget allocated to the regions “Vienna” and “Other” will be shown for WWTF projects and to the regions “Vienna”, “Lower Austria” and “Other” for Joint Projects. - For “regular” WWTF projects, at least 80% (i.e., ≥80%) of the requested funding must be allocated to the region “Vienna”. Up to 20% (i.e., <20%) may be allocated to other partner(s) (including partners in Lower Austria). - For Joint Projects, the budget allocated to the region “Vienna” must be ≥50%. The share of the budget allocated to the region “Lower Austria” must be between 20–50% (i.e., >20% and <50%). Maximum 20% (i.e., £ 20%) may be allocated to further partner(s) located in other regions (“Other”). - The proportions of the budget allocated to personnel and non-personnel costs are also shown. Please note that, in this call, non-personnel costs should not exceed 40% of the total budget. - The system will display an alert if the inserted amounts exceed the permitted funding distribution across regions or cost types. - Please note that changing the proposal between “WWTF Project” and “Joint Project” types will reset the budget table due to differing budget distribution requirements. **Explanation of Cost Planning** *(max. 750 characters)* Outline details about the planned allocation of resource allocation as requested in the budget.In the case of an invitation to submit a full proposal, there should not be significant changes in the requested budget compared to the short proposal. Exceptions are permitted but require justification.
# LS25 / Short Proposal / SignaturesSubmission of the proposal requires the signatures of the authorized person(s) at the host institutions of each of the PI&C and co-PIs (“Authorization”). Please consult your institutional research services regarding the person mandated to sign the proposals and plan sufficient time to obtain their signatures.
1. Enter the name of each authorized person in the online form. This information will be included in the PDF to be signed. 2. Download the PDF using the link “You can generate the signature sheet here”. 3. Signatures may be provided in various formats: - - Scanned or physical signature - Electronic signature (e.g., A-Trust, Handysignatur). Please note that electronically signed PDFs cannot be merged into a single document.Unlike proposals in the previous Submission System, signatures from the core team are no longer required in the new Funding Portal.
# LS25 / Short Proposal / Proposal submission Once all symbols in all chapters are marked by green checkmarks, the proposal can be submitted. The “Submit” button is at the bottom of the “Signatures” chapter. The PI&C will receive an automatic confirmation email when the Funding Portal receives the completed submission. Please check your emails after hitting the submit button. **If you do not receive a confirmation email, please get in touch with the Call Manager.**You can access your submitted proposal as PDF on the page “My Proposals and Roles”.
**No changes are possible after the project has been submitted.** After the indicated deadline, submission is no longer possible. Unsubmitted proposals will be excluded from the ensuing evaluation process and deleted shortly after the submission deadline.
# LS25 Precision Medicine / Full Proposal / Submission Guideline This section is a guide to using WWTF’s Funding Portal. It is intended for applicants who have been invited to submit a full proposal in the Life Sciences 2025 Call - Precision Medicine. # LS25 / Full Proposal / Key information ##### Submission of full proposals - All proposals must be submitted electronically via the [WWTF’s Funding Portal](https://fundingportal.wwtf.at/). The Funding Portal will automatically save your entries and changes. You can pause data entry at any time. All information will be available again upon your next login. - All core team members (i.e., coordinating PI and co-PIs) can contribute to and edit the proposal before its submission. However, only one person can edit the proposal in the Funding Portal at any time.Please note that only the coordinating PI (PI&C) can submit the proposal.
- All sections of the proposal must be written in English. - The length of the proposal is determined by character counts (including spaces) and page limits in case of uploads in the Funding Portal. - The full proposal will be assessed by **experts in the specific topics of the proposal**. These experts will provide written assessments for the jury panel, whose collective expertise covers a range of topics in this call.Please write the full proposal in a way that allows assessment by both expert reviewers and a broad high-level jury panel.
##### Overview of the full proposal phase - Deadline for submission of full proposals: October 7, 2025, 2pm CET - Assessment of full proposals through external written reviews - Applicant response phase: between February 9-20, 2026 (exact dates TBD) - Meeting of jury panel to select projects for funding: late February 2026 - Funding decision of WWTF's Board of Directors: March 2026 # LS25 / Full Proposal / Accessing your proposal 1. Go to [https://fundingportal.wwtf.at/](https://fundingportal.wwtf.at/) 2. Login with your credentials 3. You will see an overview of your proposal(s) and role(s) under the menu “My Proposals & Roles" [](https://wiki.wwtf.at/uploads/images/gallery/2025-03/nWDDNxOkZZEGybZW-image.png) - **A **Click on “Short Proposal” to download a PDF of your submitted short proposal - **B **Click on the project title to edit the full proposal - **C** Click on your role to edit your specific role in this proposal # LS25 / Full Proposal / Update information about PIsContact details, CV, and information about your role in the project have been automatically transferred from the short proposal to the full proposal. Please ensure the information in the tab "My Profile" and "My Roles" is up-to-date. Only update information if required.
##### Step 1: Update your profile information if required Upon login, go to “My Profile” in the top menu to update your profile. To update your CV, delete the previous document and upload a new CV as PDF. The requirements regarding the CV in the full proposal are the same as those in the short proposal . Please review these requirements [here](https://wiki.wwtf.at/books/archiviert-life-sciences-call-2025-precision-medicine/page/ls25-short-proposal-cv-and-list-of-publications). ##### Step 2: Update information about your specific role in the proposal if relevant Go to “My Proposal & Roles” in the top menu. Under “My Roles”, click on your role below the title of the proposal. - - You can update the personal information by clicking on “Refresh from profile”. The system will check if there is new information in “My Profile” and update this section accordingly. Should you have uploaded a new CV in "My Profile", it will now be transferred to the full proposal. - The requirements regarding the description of your specific role in the full proposal are the same as those in the short proposal. Please review these requirements [here](https://wiki.wwtf.at/link/839#bkmrk-step-3%3A-complete-you). *Please note that the information entered here should be specific to the project. If you are participating in multiple proposals that require different subsets of your expertise, please tailor the information according to the project.* # LS25 / Full Proposal / Overview of chapters The full proposal is comprised of six chapters, each under a separate tab: - [Basic Information](https://wiki.wwtf.at/link/926#bkmrk-basic-information "LS25 / Details of chapters") - [Personnel and Institutions](https://wiki.wwtf.at/link/926#bkmrk-7.2-personnel-and-in) - [Project](https://wiki.wwtf.at/link/926#bkmrk-project) - [Budget](https://wiki.wwtf.at/link/926#bkmrk-7.4-budget) - [Signatures](https://wiki.wwtf.at/books/archiviert-life-sciences-call-2025-precision-medicine/page/ls25-full-proposal-signatures "ICT25 / Signatures") A chapter with a red alert symbol indicates that it is incomplete. Within the marked chapter, click on the red symbol(s) beside individual sections to highlight the fields requiring attention. A green checkmark symbol indicates that the information in the chapter is complete.Please note that the symbols might not refresh immediately even if the information in the chapter is complete. Changing to another chapter and going back to the other will refresh the symbol.
# LS25 / Full Proposal / Details of chapters ##### Basic InformationThe name, acronym, nominated scientific disciplines, project duration and type of project (regular WWTF Project or Joint Project) can **no longer** be changed.
- **Keywords**: These will help the WWTF identify appropriate reviewers for your proposal. Keywords may still be edited or added. - **Suggested peer reviewers**: Applicants must suggest **five** international peers whom they deem qualified to review the proposal. To enable the selection of a balanced set of reviewers, please provide keywords or phrases to describe the reviewers’ fields of expertise. Suggested reviewers must be based **outside of Austria** and have **no conflict of interests** with project applicants (complete team and collaborators). Persons with whom the project applicants have worked together (joint publications, research cooperations, etc.) in the last five years will not be considered. Please note that the WWTF will decide if suggested peers will be contacted for reviewing, and WWTF may take different reviewers to those you suggested. As a rule, WWTF will include a maximum of two reviewers suggested by the applicants. The other reviewers are suggested by the jury and/or WWTF office to avoid bias. - **Excluded peer reviewers**: Applicants may, without stating any reasons, exclude up to three individuals from reviewing their proposal. The names of the peer reviewers suggested and excluded by the applicants will be shared with the jury panel but not disclosed to potential reviewers themselves. Each proposal is reviewed by no less than three reviewers. ##### Personnel and InstitutionsThe addition, removal, or substitution of core team members (PI&C, co-PIs) are **not** permitted at this stage. WWTF may make exceptions in well-argued circumstances (e.g., a co-PI moving to an institution abroad or leaving the academic field).
Should well-justified changes in the core team be necessary, please contact WWTF. WWTF reserves the right to exclude projects from further evaluation in cases in which PIs can no longer be part of the project team. **Further partner institutions**: Collaborating institutions beyond those of the core team members can be added in this stage. Please note that every person involved in the project must be linked to an institution in order to allow indication of time commitment and salary in the “Budget” section. A **signature** will be required from the authorizing persons at the core team members’ institutions and at all further partner institutions. A maximum of **five different institutions** (including those of the core team members) is permitted. Should a project be funded, the addition of further collaborations will be possible. ##### Project This is the main section of the proposal that requires elaboration of the project’s scientific content.Please note that the character limit includes spaces.
**Lay summary** (*max. 1,000 characters*) Please provide a description of your proposed research that is suitable for the general public. This will primarily be used by WWTF for communicating your work to non-experts for fundraising and public relations purposes. **Scientific abstract** (*max. 2,000 characters*) Please provide a concise scientific abstract of the project. This will be used in approaching reviewers. The abstract has been taken automatically from the short proposal, but may be edited for the full proposal. **Work program** (*max. 15 pages*)Please use the template provided for download in the WWTF Funding Portal.
The bold headings are mandatory. Each subheading must be addressed explicitly, in a format and order of the applicants’ choosing. Use a common font type (such as Arial, Source Sans Pro) and font size 11pt. Line spacing should be between 1.3 and 1.5. Do not add any headers or footers (such as page numbers, proposal number, title of proposal), as this information will be added automatically to the file upon upload. Figures, tables, etc. may be included. A final PDF of a maximum of 15 pages, including figures and references, is permitted. Applicants should allocate this space as they see fit. **1. Introduction and background** a. Subject of the research b. State of the art and key clinical/scientific challenges **2. Hypotheses and objectives** a. Research questions and/or hypotheses b. Objectives of the project **3. Innovativeness and relevance** a. Innovativeness of the proposed research b. Contribution and relevance to the field of precision medicine **4. Research plan and methods** a. Preliminary data relevant to the project (if available) b. Description of the patient cohort (including sample numbers, stage of sample collection/patient recruitment, power calculations, etc.) c. Sex and gender aspects of research d. Research plan, including milestones and deliverables e. Research and analysis methods (including necessary expertise within project team) f. Interdisciplinary collaborative aspects **5. Project management and feasibility** a. Feasibility, risk management and mitigation strategies b. Data management (including protocols, data sharing, dissemination, etc.) **6. Key references** - - Please include the DOI for each reference **Ethical considerations** (*max. 800 characters*) If available, the ethical approval (final or preliminary) or confirmation of submission of an ethical approval should be submitted. If an ethical approval for the proposed work has yet not been granted, applicants must provide a timeline and an explanation of the feasibility of obtaining the necessary ethical approvals. In the latter case, applicants commit themselves to obtaining the required permits to commence the project in a timely manner, should it be selected for funding.Upon selection for funding, submission of the final ethical approvals to WWTF is a prerequisite for the funding contract. As projects must start no later than 6 months after funding approval, grantees must ensure that ethical approvals are submitted to WWTF in time for the funding contract to be concluded.
**Data management** (*max. 800 characters*) In case of funding, a data management plan must be stepwise developed over the runtime of the project. At the full proposal stage, we encourage applicants to consider and briefly address the following points as appropriate: - What kind of accompanying metadata and documentation will help others identify, discover, reuse and/reproduce the research data? - How will data for sharing and preservation be selected? - When will data be shared? - In which repository will data be archived? How long will data be retained? - What persistent identifiers (e.g., DOI) and usage licenses (e.g., CC BY) will be used? **Use of generative AI **(max. *500 characters*) Please describe if and how GenAI has been used in developing your research proposal. [Please see further details here](https://wiki.wwtf.at/books/archiviert-life-sciences-call-2025-precision-medicine/page/ls25-use-of-generative-ai-in-the-application-process "LS25 / Use of generative AI in the application process"). ##### Budget Please note the following guidelines for the budget: - Maximum 15% difference between the budgets of the short and full proposals is permitted. - Non-personnel costs should not exceed 40% of the total requested budget. **Personnel costs** - Core team members of the short proposal are automatically listed in the respective table. - Click “Additional person” to individually add all persons who will work on the project. Please provide their name or select “is N.N.” if the role is to be filled (e.g., PhD candidate, Post Doc). Indicate the affiliation and staff category of each person using the dropdown menu. If an affiliation is not listed, return to the section “Personnel and Institutions” and add the respective institution. Each person must be assigned to an institution. - Specify if the person will be financed by WWTF or contribute on an in-kind basis, and indicate their yearly time commitment to the project for each year (full time equivalents). A mixture of WWTF and in-kind financing is permitted. - For persons financed by WWTF, enter the annual salary that corresponds to 100% annual gross costs in the first year of the project (employer and employee costs = gross costs / “Brutto-Brutto-Jahresgehalt”). Please note that PhD positions are often calcuated on a 75% employment basis. The total funding requested for each person will be automatically calculated. - For personnel costs, an annual 3.5% p.a. increase in salary over the lifetime of the project has been pre-programmed. This is intended to assist with planning only, and actual salaries should be paid according to institutional or collective agreements. Please use baseline salaries according to the date you expect to start the project. (The project should start the latest September 2026.) Please contact your institutional research support services in this matter. **Non-personnel costs** - Add rows to provide a concise overview of all non-personnel costs directly related to the project. Please select the institution and cost category from the dropdown menus. If an affiliation is not listed, return to the section “Personnel and Institutions” and add the respective institution. - Costs for basic infrastructure (rent, telephone) are not permitted. Costs for larger equipment essential for the project may only be requested on a pro rata basis that also takes into consideration the proportion of time that the equipment will be used for this project. - WWTF strongly encourages open access publications. Costs for Article Processing Charges (APCs) may be requested. - Costs for data management purposes (e.g., curation, storage) are eligible. **Budget per region** - The share of the budget allocated to the regions “Vienna” and “Other” will automatically be shown for WWTF projects, and to the regions “Vienna”, “Lower Austria” and “Other” for Joint Projects. - For regular WWTF projects, at least 80% of the requested funding must be allocated to the region “Vienna”. Up to 20% may be allocated to other partner(s), including partners in Lower Austria. - For Joint Projects, the budget allocated to the region “Vienna” must be at least 51%. The share of the budget allocated to the region “Lower Austria” may range from 21% to 49%. Up to 20% may be allocated to any further partner(s) located in other regions (“Other”). **Cost overview** - Enter the overhead rate for each institution. WWTF permits a maximum of 20% overheads costs. Please consult each institutions’ research services to ensure compliance with all institutions’ internal regulations. **Explanation of Cost Planning** (*max. 1,500 characters*) - Please provide an explanation of cost planning principles, also indicating access to resources that are already available. **Disclosure of other applications for funding** (*max. 750 characters*) - If you have applied for funding for this project (or parts thereof) at other organisations, please indicate this here. This will not impact the evaluation of this proposal. - Double submissions will be reviewed by the FWF. This means that the FWF will receive the list of projects and check whether a similar project has already been submitted to the FWF. - WWTF does not allow double funding. If your proposal is selected for funding by both WWTF and another funding organisation, we will ask you to decide which funding you will accept. # LS25 / Full Proposal / SignaturesSubmission of the full proposal requires the signatures of the authorized persons at all participating institutions ("Authorizations"). This includes the host institutions of the **core team members**, as well as all **further partner institutions**.
- Please consult your institutional research services regarding the person mandated to sign the proposals and plan sufficient time to obtain their signatures. - Make sure that all participating institutions have been added in the “Personnel and Institutions” section before downloading the signatures sheet. - Enter the name of each authorized person in the online form. This information will be included in the PDF to be signed.For authorizations from the Medical University of Vienna, please delete the name of the Vice Rector. Instead, for each core team member and further partner institution at the Medical University of Vienna, please insert the name and position of the head of their department/institute.
- Download the PDF using the link “You can generate the signature sheet here”. - Signatures may be provided in various formats - Add a scanned or physical signature, and upload the form; or - Insert an electronic signature (e.g., A-Trust, Handysignatur) and upload the form. Please note that electronically signed PDFs cannot be merged into a single document - The signed signature pages can only be accessed via a link in the final project PDF.Please ensure signatures are dated. Undated signatures and re-use of signatures from the short proposal will not be accepted.
Unlike in the previous Submission System, signatures from the core team are no longer required in the new Funding Portal.
# LS25 / Full Proposal / Proposal submission Once all symbols in all chapters are marked by green checkmarks, the proposal can be submitted. The “Submit ” button is at the bottom of the “Signatures” chapter. The PI&C will receive an automatic confirmation email when the Funding Portal receives the completed submission. Please check your emails after clicking the submit button.If you do not receive a confirmation email, please get in touch with the [Call Manager](https://wiki.wwtf.at/books/archiviert-life-sciences-call-2025-precision-medicine/page/ls25-precision-medicine-contacts "LS25 Precision Medicine / Contacts")s.
You can access your submitted proposal as PDF on the page “My Proposals and Roles”.
No changes are possible after the project has been submitted. After the indicated deadline, submission is no longer possible. Unsubmitted proposals will be excluded from the ensuing evaluation process.
# LS25 / Full Proposal / Applicant Response Phase **Applicant Response Phase **(10th - 17th of February 2026, 2pm (CET)) The purpose of the applicant response step is to allow the core team to correct any factual errors or conceptual misunderstandings in the external peer reviews. The applicants should respond directly to reviewer comments in a constructive manner. **Scope of applicant response** As much as possible, the applicant response should refer to parts of the full proposal where the reviewer’s concerns are already addressed. Only where necessary and appropriate, should references to peer-reviewed publications in order to correct any factual inaccuracies in the reviews be provided. In addition to providing the DOI, applicants should clearly specify the section (figure, data, text) of the publication that supports their response. Pictures, graphs, or other documents themselves cannot be inserted or attached. - The applicant response must not be regarded as an opportunity to extend the full proposal. Elaboration upon aspects of the full proposal with more detail is not permitted. - New information, including new research results and methods, should not be provided. - Applicant responses should not include references to any new awards, appointments, or publications that may have occurred since the submission of the full proposal. - Response should be clearly presented, objective and concise. The limit of **3,000 characters** (with spaces) applies for all teams. Thus, only include information that clearly addresses the points of the reviewer.Both the scientific workplan and CVs are assessed as at the time of the full proposal submission, and therefore no updates should be provided. Such additional information will not be considered by the jury members.
**Process for applicants** - All steps of the applicant response phase will proceed over the WWTF Funding Portal. - Applicants will be given 7 calendar days to respond to the peer reviews (10th - 17th February 2026, 2pm (CET)). - All core team members will receive an email notification from the Funding Portal when the applicant response phase is open. Core team members are therefore strongly advised to regularly check their provided email address during the indicative time period. - All core team members will have access to the anonymized reviews for their proposal and have the opportunity to edit the response.Only the PI&C can submit the final applicant response.
**What will happen to the applicant response?** - The applicants' response will be provided to the panel after the panel has received all external reviews and prior to the panel meeting to determine funding. - Applicants' responses will not be viewed by the external reviewers. - The jury panel will be briefed about the scope of permitted responses and informed to ignore responses that fail to observe these guidelines. Panel members will consider how well applicants have addressed any concerns raised by the reviewers and will consider additional valid evidence provided within the response. - Please note that, depending on its content and quality, the applicant response can potentially have positive and/or negative effects on the evaluation of the proposal by the jury panel.Submission of a response to reviews is not compulsory. However, the jury panel will be informed that all teams were provided with the opportunity to respond to reviews.
# LS25 Precision Medicine / Important documentsThe following documents provide information on general guidelines and processes of the WWTF
| [**WWTF Funding Guideline**](https://wwtf.at/upload/wwtf_forderrichtlinie_08112021_final(1).pdf) | General Guideline for WWTF funding activities |
| [**Guideline for Good Scientific Practice**](https://www.wwtf.at/upload/broschure_gwp-richtlinien_web_2017.pdf) | Guidelines by the Austrian Agency for Research Integrity |
| [**Open Science Policy**](https://www.wwtf.at/upload/wwtf_open-science-policy_09032022.pdf) | Open Science Policy of WWTF |
| [**Gender Equality Strategy & Plan**](https://www.wwtf.at/upload/wwtf-gender-equality-strategy-and-plan_final.pdf) | Gender Equality Strategy & Plan of WWTF |
| [**Reporting and Accounting Guideline**](https://wwtf.at/upload/anhang_berichtswesen-und-abrechnungsmodalitaten_17072024.pdf) | Specifies reporting and accounting for funded projects |
| [](https://wiki.wwtf.at/uploads/images/gallery/2025-01/MvZZhlANPDDojp1w-liu-kleiner.jpg) | [](https://wiki.wwtf.at/uploads/images/gallery/2025-01/ccESkl6DFZfoVOzo-bec0017-ps.jpg) |
| Grace Liu
| Petra Steinkogler
|