# LS25 Precision Medicine / Call Specifications

This document specifies the processes, criteria, and instrument of the Life Sciences Call 2025 in Precision Medicine. It is intended for applicants wishing to submit a proposal in this project call.

# LS25 / Scope of the call

<p class="callout info">This “Precision Medicine” call is issued within the WWTF Life Sciences Programme. This call is open to research projects that draw upon precision medicine approaches to improve prevention, diagnosis or treatment of a human disease.</p>

Please consider the following **key requirements** regarding scope of projects in this call:

- Projects should advance understanding of a clinically relevant research question by contributing to, or utilising, insights based on high-quality datasets from well-defined patient cohorts.
- Anticipated research outcomes should have clear implications for improving the prevention, diagnosis or treatment of a human disease.
- Projects should contribute to understanding of disease pathogenesis or treatment-relevant biological mechanisms.
- Research teams should demonstrate interdisciplinarity across clinical, biological, data analysis and/or engineering expertise.
- Consideration of the role of sex and gender in the development and treatment of diseases is essential.

Within the domain of precision medicine, this call is open to projects with diverse aims and methodologies. The following research directions are considered **within the scope** of this call. Please note that this is not a comprehensive overview and that all projects must demonstrate fulfilment of the above key requirements.

- Projects may aim to develop novel targeted therapies based upon understanding of disease pathogenesis and patient heterogeneity.
- Projects may involve the development of novel preclinical models based on patient cohort data to improve understanding of the pathogenesis and/or treatment outcome of a human disease.
- Projects may focus on understanding disease susceptibility in heterogeneous populations and seek to contribute to the development of targeted preventive interventions.
- New patient datasets may be generated or assembled as part of the project, or projects may draw on existing datasets. Should new datasets be generated, demonstration of access to well-characterised cohorts and feasibility of attaining the required ethical approvals in a timely manner will be required. Please see the [requirements](https://wiki.wwtf.at/books/archiviert-life-sciences-call-2025-precision-medicine/page/ls25-guidelines-for-good-scientific-practice-and-ethics) in this call regarding ethical approvals.

Please note that the following types of projects are deemed to be **outside the scope** of this call:

- Public health studies that do not contribute to mechanistic understanding of a disease or therapeutic treatment.
- Basic biomedical research and technology development in the absence of specific clinical rationale and implications.
- Clinical trials of medicinal products.

# LS25 / Structure of the Call

<p class="callout info">This call follows a two-stage selection process, consisting of a short proposal and full proposal phase.</p>

- **Short proposals**: Applicants provide a short description of the project’s background, objectives and methodology, along with a budget overview.

<p class="callout danger">Short proposal deadline: May 6th, 2025, 2pm CET </p>

- **Full proposals:** Proposals selected by the jury are invited to submit an extended proposal that includes a detailed project budget. Applicants will have the opportunity to respond in writing to the external reviews of the full proposal.

<p class="callout danger">Full proposal deadline: October 7th, 2025, 2pm CET  
</p>

<p class="callout danger">Applicant response phase: February 9th – 20th, 2026 (*Applicants invited to submit a full proposal will be notified of exact dates in late January)*</p>

# LS25 / Submission

<p class="callout info">Applications must be submitted via the [WWTF Funding Portal](https://fundingportal.wwtf.at/). All application information will be processed via this system.</p>

- All core team members, i.e., coordinating PI (PI&amp;C) and co-PIs, may access and edit the proposal. **Only the PI&amp;C can submit the proposal.**
- The structure of the proposal and steps for completing the application in the WWTF Funding Portal are described in more detail in the Submission Guideline, which will be made available in March 2025.
- **Signatures of the authorized signatory at participating institutions** (“authorizations”) are required in the application process (only for institutions of core team members in the short proposal phase, also for all partner institutions in the full proposal phase). Please contact your institution’s research service in advance and inform yourself about your institute’s internal processes and timelines.
- Applications must be written in **English**.

# LS25 / Eligibility and roles of applicants

<span lang="EN-GB">The general eligibility of applicants is specified in the </span><span lang="DE">[<span lang="EN-GB">WWTF Funding Guideline</span>](https://wwtf.at/upload/wwtf_forderrichtlinie_08112021_final(1).pdf) *(in German only)*</span><span lang="EN-GB">.</span>

<span lang="EN-GB" style="mso-ansi-language: EN-GB;">A project’s **core team** may include **up to** **three Principal Investigators (PIs).** This includes a PI&amp;C and up to two co-PIs. </span>

- <span lang="EN-GB" style="mso-ansi-language: EN-GB; mso-bidi-font-weight: bold;">Core team members may share equal management and scientific roles in the project.</span>
- <span lang="EN-GB" style="mso-ansi-language: EN-GB;">The core team must have an excellent scientific track record that demonstrates the ability to conduct the proposed research project.</span>
- WWTF <span lang="EN-GB" style="mso-ansi-language: EN-GB;">especially encourages young and female scientists to apply as PI.</span>
- **<span lang="EN-US">Each core team member must submit a CV</span>**<span lang="EN-US">, which will form part of the evaluation.</span>
- A researcher may appear as a core <span lang="EN-US">team member (i.e., PI&amp;C, co-PI) in a maximum of two proposals in this call. In case of three or more proposals with the same PI, WWTF will accept the first two proposals submitted. Involvement in</span><span lang="EN-GB"> other past / ongoing / granted WWTF projects does not impact upon eligibility to apply in this call.</span>

<span lang="EN-GB" style="mso-ansi-language: EN-GB;">One PI must be designated as **PI&amp;C** (PI and coordinator). </span>

- <span lang="EN-GB" style="mso-ansi-language: EN-GB; mso-bidi-font-weight: bold;">For legal and administrative reasons (funding contract, reporting), WWTF requires a PI&amp;C to be named. The PI&amp;C will be the contact person for WWTF regarding all aspects of the project.</span>
- <span lang="EN-GB" style="mso-ansi-language: EN-GB; mso-bidi-font-weight: bold;">The </span><span lang="EN-GB" style="mso-ansi-language: EN-GB;">PI&amp;C<span style="mso-bidi-font-weight: bold;"> must have an affiliation at a Viennese research institution, which will serve as a legal contract partner. This also applies to researchers moving to Vienna, who must have a Viennese affiliation in case of funding.</span></span>
- <span lang="EN-GB" style="mso-ansi-language: EN-GB;">The PI&amp;C should be an expert in an area relevant to the topic of the proposal. He/she must have an excellent scientific track record and a proven capability to manage projects. </span>

<span lang="EN-GB" style="mso-ansi-language: EN-GB;">Up to two **co-PIs** may also be named in the core team. </span>

- <span lang="EN-GB" style="mso-ansi-language: EN-GB; mso-bidi-font-weight: bold;">WWTF recognizes that co-PIs may have equally significant scientific roles in the project. However, the PI&amp;C will be regarded as the main contact person for the project.</span>
- <span lang="EN-GB" style="mso-ansi-language: EN-GB; mso-bidi-font-weight: bold;">Co-PIs may be based in Vienna, Lower Austria or elsewhere (in Austria or internationally) in fulfilment of the requirements of regular WWTF projects or Joint Projects (see below). </span>

<span lang="EN-GB" style="mso-ansi-language: EN-GB;">Additional **project partners and collaborators** are permitted in the research team. They can be added by name in the full proposal stage. </span>

- <span lang="EN-GB" style="mso-ansi-language: EN-GB; mso-bidi-font-weight: bold;">Non-academic collaboration partners (e.g., NGOs) may be part of the research team. How-ever, the core team members and majority of additional team members in the proposal should have an academic background.</span>
- <span lang="EN-GB" style="mso-ansi-language: EN-GB; mso-bidi-font-weight: bold;">Industry partners are not eligible for funding, but may partake with in-kind or financial contribution.</span>

**<span lang="EN-GB" style="mso-ansi-language: EN-GB;">Research partners outside Vienna: </span>**

- <span lang="EN-GB" style="mso-ansi-language: EN-GB;">For regular WWTF projects, project partners outside of Vienna may receive up to 20% (i.e., &lt;20%) the total requested funding. </span>
- <span lang="EN-GB" style="mso-ansi-language: EN-GB; mso-bidi-font-weight: bold;">This call operates under the [“Joint Projects” agreement with the Province of Lower Austria](https://wiki.wwtf.at/books/archiviert-life-sciences-call-2025-precision-medicine/page/ls25-joint-projects-with-partners-in-lower-austria "ICT25 / Specifics of Joint Projects with partners in Lower Austria"). </span>

# LS25 / Joint Projects with partners in Lower Austria

<p class="callout info"><span lang="EN-GB" style="mso-ansi-language: EN-GB;">WWTF welcomes **Joint Project (JP) applications** between Viennese and Lower Austrian universities and research institutions in this call. </span></p>

<span lang="EN-GB" style="mso-ansi-language: EN-GB;">The aims of this initiative are to promote research cooperation between Lower Austria and Vienna on equal terms and to strengthen cooperation of research institutions in the Vienna region. </span>

- <span lang="EN-GB" style="mso-ansi-language: EN-GB;">To incentivize the cooperation, the total maximum funding amount for a JP consortium is € 1.1 million (i.e., an additional € 100,000 compared to the maximum for a regular WWTF project).</span>
- The PI&amp;C must be affiliated to a research institution in Vienna.
- <span style="font: 7.0pt 'Times New Roman';"> </span><span lang="EN-GB" style="mso-ansi-language: EN-GB;">At least one co-PI must be affiliated to a research institution in Lower Austria.</span>
- The share of the overall funding allocated to research institutions in Lower Austria must be &gt;20% and &lt;50%. In case that the Lower Austrian share is ≤20%, the project is considered as a regular WWTF project and is not eligible for the higher maximum funding amount.
- <span lang="EN-GB" style="mso-ansi-language: EN-GB;">The Lower Austrian share is financed by the Province of Lower Austria. Hence, the Lower Austrian project partner must comply with the [Lower Austrian Culture ](http://www.noe.gv.at/noe/Kunst-Kultur/Richtlinien_zum_Noe_Kulturfoerderungsgesetz_1996_3.pdf)</span><span lang="EN-GB" style="mso-ansi-language: EN-GB;">[Promotion Act 1996 and the directives](https://www.noe.gv.at/noe/Wissenschaft-Forschung/Richtlinien_zum_Noe_Kulturfoerderungsgesetz_1996_2.pdf) issued on the basis thereof. Further details will be provided in the funding contract.</span>
- Partners outside Vienna or Lower Austria are also possible and may request up to 20% (i.e., &lt;20%) of the total budget. However, the share of the budget allocated to partner(s) in Vienna must be at least 50% (i.e., ≥50%).
- Regional branches of Viennese Institutions (e.g., BOKU, VetMed, AIT) located in Lower Austria are considered as Vienna-based in the context of WWTF funding activities.

<p class="callout danger">A conversion between JPs and regular WWTF projects is not possible between the short and full proposal phases.</p>

<div id="bkmrk-" style="mso-element: footnote-list;"><div id="bkmrk--1" style="mso-element: footnote;"></div></div>

# LS25  / Structure of the proposal

<span lang="EN-US" style="mso-ansi-language: EN-US;">The content and structure of the proposal are defined and specified in the Submission Guideline, which will be made available in March 2025. From March, applicants can also register and create a proposal in the [WWTF Funding Portal](https://fundingportal.wwtf.at/calls/) to find out more details. Applicants invited to submit a full proposal will be provided with an additional Submission Guide-line specifically for the second phase. An overview of the main parts of the short and full proposal is provided below:</span>

<table border="1" cellpadding="0" cellspacing="0" class="MsoNormalTable" id="bkmrk-short-proposal-full-" style="border-collapse: collapse; border: none; height: 314px; width: 104.762%;"><tbody><tr style="height: 28px;"><td style="width: 49.9403%; border: 1pt solid windowtext; padding: 0cm 5.4pt; height: 28px;" valign="top" width="302">**<span lang="EN-US" style="mso-bidi-font-size: 10.0pt; mso-ansi-language: EN-US;">Short Proposal </span>**

</td><td style="width: 50.0597%; border-top: 1pt solid windowtext; border-right: 1pt solid windowtext; border-bottom: 1pt solid windowtext; border-image: initial; border-left: none; padding: 0cm 5.4pt; height: 28px;" valign="top" width="302">**<span lang="EN-US" style="mso-bidi-font-size: 10.0pt; mso-ansi-language: EN-US;">Full proposal </span>**

</td></tr><tr style="height: 28px;"><td style="width: 49.9403%; border-right: 1pt solid windowtext; border-bottom: 1pt solid windowtext; border-left: 1pt solid windowtext; border-image: initial; border-top: none; padding: 0cm 5.4pt; height: 28px;" valign="top" width="302"><span lang="EN-US" style="mso-bidi-font-size: 10.0pt; mso-ansi-language: EN-US;">Scientific abstract</span>

</td><td style="width: 50.0597%; border-top: none; border-left: none; border-bottom: 1pt solid windowtext; border-right: 1pt solid windowtext; padding: 0cm 5.4pt; height: 28px;" valign="top" width="302"><span lang="EN-US" style="mso-bidi-font-size: 10.0pt; mso-ansi-language: EN-US;">Lay summary and scientific abstract</span>

</td></tr><tr style="height: 66px;"><td style="width: 49.9403%; border-right: 1pt solid windowtext; border-bottom: 1pt solid windowtext; border-left: 1pt solid windowtext; border-image: initial; border-top: none; padding: 0cm 5.4pt; height: 66px;" valign="top" width="302"><span lang="EN-US" style="mso-bidi-font-size: 10.0pt; mso-ansi-language: EN-US;">Project description (about 3 pages): outline of the main scientific research idea and approach</span>

</td><td style="width: 50.0597%; border-top: none; border-left: none; border-bottom: 1pt solid windowtext; border-right: 1pt solid windowtext; padding: 0cm 5.4pt; height: 66px;" valign="top" width="302"><span lang="EN-US" style="mso-bidi-font-size: 10.0pt; mso-ansi-language: EN-US;">Project description (about 12-15 pages): elaboration on the research idea and approach (template is provided) </span>

</td></tr><tr style="height: 66px;"><td style="width: 49.9403%; border-right: 1pt solid windowtext; border-bottom: 1pt solid windowtext; border-left: 1pt solid windowtext; border-image: initial; border-top: none; padding: 0cm 5.4pt; height: 66px;" valign="top" width="302"><span lang="EN-US" style="mso-bidi-font-size: 10.0pt; mso-ansi-language: EN-US;">Project core team: CVs and roles in project (mandatory template is provided)</span>

</td><td style="width: 50.0597%; border-top: none; border-left: none; border-bottom: 1pt solid windowtext; border-right: 1pt solid windowtext; padding: 0cm 5.4pt; height: 66px;" valign="top" width="302"><span lang="EN-US" style="mso-bidi-font-size: 10.0pt; mso-ansi-language: EN-US;">Project team and further collaboration partners: CVs for all core team members (mandatory template is provided) and roles in project of all team members</span>

</td></tr><tr style="height: 28px;"><td style="width: 49.9403%; border-right: 1pt solid windowtext; border-bottom: 1pt solid windowtext; border-left: 1pt solid windowtext; border-image: initial; border-top: none; padding: 0cm 5.4pt; height: 28px;" valign="top" width="302"><span lang="EN-US" style="mso-bidi-font-size: 10.0pt; mso-ansi-language: EN-US;">Budget overview </span>

</td><td style="width: 50.0597%; border-top: none; border-left: none; border-bottom: 1pt solid windowtext; border-right: 1pt solid windowtext; padding: 0cm 5.4pt; height: 28px;" valign="top" width="302"><span lang="EN-US" style="mso-bidi-font-size: 10.0pt; mso-ansi-language: EN-US;">Detailed budget </span>

</td></tr><tr style="height: 42px;"><td style="width: 49.9403%; border-right: 1pt solid windowtext; border-bottom: 1pt solid windowtext; border-left: 1pt solid windowtext; border-image: initial; border-top: none; padding: 0cm 5.4pt; height: 42px;"><span lang="EN-US" style="mso-bidi-font-size: 10.0pt; mso-ansi-language: EN-US;">Brief statement regarding ethical aspects</span>

</td><td style="width: 50.0597%; border-top: none; border-left: none; border-bottom: 1pt solid windowtext; border-right: 1pt solid windowtext; padding: 0cm 5.4pt; height: 42px;"><span lang="EN-US" style="mso-bidi-font-size: 10.0pt; mso-ansi-language: EN-US;">Ethical approval OR detailed description of ethical aspects, including feasibility and timeline for ethical approval</span>

</td></tr><tr style="height: 56px;"><td style="width: 49.9403%; border-right: 1pt solid windowtext; border-bottom: 1pt solid windowtext; border-left: 1pt solid windowtext; border-image: initial; border-top: none; padding: 0cm 5.4pt; height: 56px;" valign="top" width="302"><span lang="EN-US" style="mso-bidi-font-size: 10.0pt; mso-ansi-language: EN-US;">Signatures: from the authorising persons at the institutions of the core team members</span>

</td><td style="width: 50.0597%; border-top: none; border-left: none; border-bottom: 1pt solid windowtext; border-right: 1pt solid windowtext; padding: 0cm 5.4pt; height: 56px;" valign="top" width="302"><span lang="EN-US" style="mso-bidi-font-size: 10.0pt; mso-ansi-language: EN-US;">Signatures: from the authorising persons at all participating institutions</span>

</td></tr></tbody></table>

<p class="callout info"><span lang="EN-US" style="mso-ansi-language: EN-US;">Please note that the short proposal is intended for a jury panel with expertise covering a range of proposals, while the full proposal is primarily aimed at experts in the specific topics of the proposal.</span></p>

# LS25 / Evaluation criteria

<span lang="EN-US" style="mso-ansi-language: EN-US;">The following criteria are used in the evaluation.</span>

- **<span lang="EN-GB" style="mso-ansi-language: EN-GB;">Scope</span>**<span lang="EN-GB" style="mso-ansi-language: EN-GB;">: Is the project within the [scope](https://wiki.wwtf.at/books/archiviert-life-sciences-call-2025-precision-medicine/page/ls25-scope-of-the-call "LS25 / Scope of the call") of the call? </span>

<p class="callout warning"><span lang="EN-GB" style="mso-ansi-language: EN-GB;">Projects that do not meet the key requirements regarding scope will be rejected by the jury, regardless of scientific quality.   
</span></p>

The key criteria in the evaluation of proposals are **scientific excellence of the project and applicants**, and the r**elevance and impact** of the proposed research:

- **Scientific innovation of the proposed research project**: What is the scientific novelty and transformative potential of the proposed approach? Does the proposed research work meet the highest relevant international standards?
- **Relevance and impact**: How does the proposed work address unmet clinical needs? To what extent does the project have potential to advance prevention, diagnosis or treatment for patients? What are the mid- to long-term academic and clinical impacts of the advancements expected from the project?
- **Scientific excellence and academic potential of the applicant(s)**: Do the applicants demonstrate the expertise and potential to conduct the proposed research? Please note that scientific track record is measured according to academic age.

<span lang="EN-US" style="mso-ansi-language: EN-US;">Further criteria:</span>

- **<span lang="EN-GB">Feasibility:</span>**<span lang="EN-GB" style="mso-ansi-language: EN-GB;"> Are the timeframe and budget adequate for carrying out the project? Are the proposed resources suitable for achieving the goals? Overall, how likely is the project to contribute to advances in precision medicine?</span>
- **<span lang="EN-GB" style="mso-ansi-language: EN-GB;">Team composition and interdisciplinary collaboration: </span>**<span lang="EN-GB" style="mso-ansi-language: EN-GB;">Teams should include an appropriate mix of expertise, bringing together researchers </span><span lang="EN-GB" style="mso-fareast-font-family: 'Times New Roman'; mso-bidi-font-family: Arial; mso-ansi-language: EN-GB; mso-fareast-language: DE;">from complementary scientific disciplines if required</span><span lang="EN-GB" style="mso-ansi-language: EN-GB;">. A clear description of the roles </span><span lang="EN-US" style="mso-ansi-language: EN-US;">of the individual partners and a clear project management plan must be presented.</span>
- **Data management:** How will research data be managed and shared? Has the sustainability and impact of new resources been considered? Please also consider [WWTF’s Open Science Policy](https://wiki.wwtf.at/books/archiviert-life-sciences-call-2025-precision-medicine/page/ls25-open-science "ICT25 / Open Science").
- **<span lang="EN-GB">Consideration of gender aspects</span>**<span lang="EN-GB" style="mso-ansi-language: EN-GB;">: The relevance of potential sex-specific and gender-related aspects of the proposed projects should be considered and explained throughout the proposal. Please consider [WWTF's guidelines regarding sex and gender in research](https://wiki.wwtf.at/books/archiviert-life-sciences-call-2025-precision-medicine/page/ls25-gender-aspects-in-the-application-phase "ICT25 / Gender aspects in the application phase").</span>

<span lang="EN-GB" style="mso-ansi-language: EN-GB;">Other aspects:</span>

- **<span lang="EN-GB" style="mso-ansi-language: EN-GB;">Career breaks</span>**<span lang="EN-GB" style="mso-ansi-language: EN-GB;"> such as for parental leave, care duties and longer illnesses will be taken into account in the evaluation of the proposals. Please indicate the time periods in the applicants' CV to allow them to be considered. <span style="mso-spacerun: yes;"> </span></span>


<p class="callout info">Please note that the short proposal will be evaluated by a jury panel, who will be asked to act as generalists when evaluating proposals. In contrast, the full proposal will additionally be evaluated by reviewers with specific expertise in the topics of the proposal. Thus, an appropriate level of scientific detail should be provided at each stage to allow evaluation of the proposal by the respective audience.</p>

# LS25 / Eligible costs

<p class="callout info"><span lang="EN-US" style="mso-ansi-language: EN-US;">All costs that are directly attributable to the project and are regarded as commonly required in the respective scientific fields are eligible for funding. Please also consider your organization’s internal guidelines for eligible expenses/costs. </span></p>

#### <span lang="EN-US">Personnel costs</span>

<span lang="EN-US" style="mso-ansi-language: EN-US; mso-bidi-font-weight: bold;">WWTF is dedicated to funding researchers. Hence, the larger share of the project’s budget should be allocated to personnel costs for researchers working on the project. </span>

- <span lang="EN-GB" style="mso-ansi-language: EN-GB; mso-bidi-font-weight: bold;">Eligible forms of employment contracts are full-time and part-time contracts as well as marginal employments (“Arbeitsvertrag”). Contracts for services (“Werkvertrag”) are only permitted if the nature of the work means that it cannot be performed through employment contracts. </span>
- <span lang="EN-GB" style="mso-ansi-language: EN-GB;">All persons employed through a WWTF-funded project should receive a fair employment contract with at least a minimum wage according to the “Kollektivvertrag” (collective agreement) of the Austrian Universities / non-university research institutions. For staff employed at institutions without a collective agreement, the minimum wage should adhere to the standards of the Austrian Science Fund ([FWF salary scheme](https://www.fwf.ac.at/en/funding/steps-to-your-fwf-project/further-information/personnel-costs)).</span>
- <span lang="EN-GB" style="mso-ansi-language: EN-GB; mso-bidi-font-weight: bold;">Salaries higher than those stipulated in the collective agreement are possible, subject to the agreement from the host institution and justification based on qualifications of the researcher.<span style="mso-spacerun: yes;"> </span></span>
- <span lang="EN-GB" style="mso-ansi-language: EN-GB; mso-bidi-font-weight: bold;">Due to projected inflation rates, the budget calculation for salaries in the Funding Portal automatically includes an increase of 3.5% p.a. for the duration of the project (Full proposal budget only).</span>
- <span lang="EN-GB" style="mso-ansi-language: EN-GB; mso-bidi-font-weight: bold;">Applications for personnel costs must be in one of the following categories:</span>
    - **<span lang="EN-GB" style="mso-ansi-language: EN-GB;">Senior Personnel: </span>**<span lang="EN-GB" style="mso-ansi-language: EN-GB;">highly qualified scientists, usually permanently employed</span>
    - **<span lang="EN-GB" style="mso-ansi-language: EN-GB;">Post Doc: </span>**<span lang="EN-GB" style="mso-ansi-language: EN-GB;">or equivalent qualification, including Senior Postdocs</span>
    - **<span lang="EN-GB" style="mso-ansi-language: EN-GB;">PhD Student: </span>**<span lang="EN-GB" style="mso-ansi-language: EN-GB;">or equivalent qualification level</span>
    - **<span lang="EN-GB" style="mso-ansi-language: EN-GB;">Diploma Student</span><span lang="EN-GB" style="mso-ansi-language: EN-GB;">:</span>**<span lang="EN-GB" style="mso-ansi-language: EN-GB;"> Bachelor or Master students</span>
    - **<span lang="EN-GB" style="mso-ansi-language: EN-GB;">Office/Technician</span><span lang="EN-GB" style="mso-ansi-language: EN-GB;">: </span>**<span lang="EN-GB" style="mso-ansi-language: EN-GB;">administrative or technicians (proportional funding only)</span>

- <span lang="EN-GB" style="mso-ansi-language: EN-GB;">Personnel costs **cannot** be claimed for permanent senior staff who are already fully financed by the institution. Exceptions apply in cases where senior staff must acquire third party funding for co-financing their own position (e.g., non-university research institutions and Universities of Applied Sciences). In these cases, permanently employed senior staff may claim up to 20% of their annual salary from WWTF. </span>

#### <span lang="EN-US">Non-personnel costs</span>

<span lang="EN-US" style="mso-ansi-language: EN-US;">Running costs for basic infrastructure (telephone costs, rents) as well as costs for the acquisition of infrastructure and basic equipment are **not** eligible for funding, as these should be covered by the category “overhead costs”. The following categories of non-personnel costs are eligible for funding:</span>

- **<span lang="EN-US" style="mso-ansi-language: EN-US;">Equipment: </span>**<span lang="EN-US" style="mso-ansi-language: EN-US;"><span style="mso-spacerun: yes;"> </span>Smaller equipment can be purchased with funds from the grant</span><span lang="EN-GB" style="mso-ansi-language: EN-GB;">. This includes devices up to € 1,500 each, as well as software specific to the projects.</span>**<span lang="EN-GB" style="mso-ansi-language: EN-US;"> </span>**<span lang="EN-GB" style="mso-ansi-language: EN-GB;">General office software is not eligible for funding. Funding by WWTF in project calls is not intended to cover investment in general and larger infrastructure. However, pro rata depreciation rates over the project duration for equipment necessary to the project may be funded.</span>
- **<span lang="EN-US" style="mso-ansi-language: EN-US;">Consumables</span>**<span lang="EN-US" style="mso-ansi-language: EN-US;">: Costs for project-related expenses like </span><span lang="EN-GB" style="mso-ansi-language: EN-GB;">consumables are permitted. WWTF does not fund consumables that are general and not project-specific (e.g., paper, printer toner).</span>
- **<span lang="EN-US" style="mso-ansi-language: EN-US;">Travel costs</span>**<span lang="EN-US" style="mso-ansi-language: EN-US; mso-bidi-font-weight: bold;">: Costs for travel and accommodation for scientific meetings and conferences, field work, expeditions </span><span lang="EN-GB" style="mso-ansi-language: EN-GB;">may be funded. Please also consider the regulations of your organization for travel costs.</span>
- **<span lang="EN-US" style="mso-ansi-language: EN-US;">Publication costs: </span>**<span lang="EN-US" style="mso-ansi-language: EN-US;">Costs incurred for publication activities, e.g., printing costs, article processing charges (for open science), etc. are allowed. This also includes costs for archiving research data in open repositories. </span><span lang="EN-GB" style="mso-ansi-language: EN-GB;">Please also consider [WWTF's Open Science Policy](https://wwtf.at/upload/wwtf_open-science-policy_09032022.pdf).</span>
- **<span lang="EN-US" style="mso-ansi-language: EN-US;">Workshop/conferences</span>**<span lang="EN-US" style="mso-ansi-language: EN-US; mso-bidi-font-weight: bold;">: Costs for organizing events, workshops, and conferences as well as for hosting invited speakers are eligible.Other costs: Third-party costs, namely, for external collaboration, consulting, studies, and software development may be funded to a limited extent. In general, individuals should be predominantly funded through employment contracts at the participating institutions and not through other types of employment. Under special conditions, costs for childcare and/or career coaching for female WWTF-funded personnel may be requested to a small degree.</span>

<p class="callout warning"><span style="text-indent: -18pt;">Non-personnel costs should not exceed 40% of the overall budget.</span></p>

#### <span lang="EN-US">Indirect costs (overheads)</span>

<p class="callout info"> WWTF pays a maximum of 20% overhead.</p>

Overhead is calculated as a percentage of the direct costs of the project (i.e., personnel + non-personnel costs). Please note that WWTF offers the maximum 20% overhead lump sum to compensate for all administration costs. This means that flat fees for payroll or project accounting are not eligible. The total funding volume is calculated as direct plus indirect costs.

Applicants are required to comply with the overhead regulations of the involved institutions.

# LS25 / Gender aspects in the application phase

<span lang="EN-US" style="color: black; mso-themecolor: text1; mso-ansi-language: EN-US;">WWTF’s [Gender Strategy and Gender Equality Plan ](https://www.wwtf.at/upload/wwtf-gender-equality-strategy-and-plan_final.pdf)must be considered throughout the application</span><span lang="EN-US" style="mso-ansi-language: EN-US;">. Please note that WWTF requests jury members and reviewers to take into account both gender and specific roles in research team composition, as well as gender in research content during evaluation processes.</span>

<span lang="EN-US" style="mso-ansi-language: EN-US;">The following questions should be considered during development of the proposal:</span>

**Equal opportunities in research**

- <span lang="EN-GB" style="font-weight: normal;">Please take into consideration gender balance/equality in the project consortium at all levels, including in decision-making positions, e.g., what steps have been taken to approach / achieve it?</span>
- Do working conditions allow all members of staff to combine work and family life in a satisfactory manner?
- Are there mechanisms in place to manage and monitor gender equality aspects, e.g., workforce statistics?

**<span lang="EN-GB">Gender in research content and in the research ideas phase</span>**

- <span lang="EN-GB" style="font-weight: normal;">If the research involves humans as research objects, has the relevance of gender to the research topic been analysed?</span>
- If the research does not directly involve humans, have potentially differentiated relations of men and women to the research subject (e.g., relevance, impact of findings) been sufficiently considered?
- Have literature and other sources relating to gender differences in the research field been consulted?

**<span lang="EN-GB">Proposal phase</span>**

- <span lang="EN-GB" style="font-weight: normal;">Does the methodology ensure that (possible) gender differences will be investigated: that sex/ gender differentiated data will be collected and analysed throughout the research cycle and will be part of the final publication?</span>
- <span lang="EN-GB" style="font-weight: normal;">Does the proposal explicitly and comprehensively explain how gender issues will be handled?</span>
- If there are no identifiable gender aspects after a detailed review by the applicants, this must be justified, e.g., by providing reasons to demonstrate that no sex, gender, and other relevant differences have been found.

**<span lang="EN-GB">Research phase</span>**

- <span lang="EN-GB" style="font-weight: normal;">If there are further aspects of the project in which sex/gender could be a factor (e.g., samples, testing groups), are these gender-balanced?</span>
- Are questionnaires, surveys, focus groups, etc. designed to unravel potentially relevant sex and/or gender differences in your data?
- <span lang="EN-GB" style="font-weight: normal;">Is data analysed according to the sex variable? Are other relevant variables analysed with respect to sex? </span>

---

**Further resources**

- Gender in Research Toolkit by Yellow Window: [https://www.yellowwindow.com/genderinresearch](https://www.yellowwindow.com/genderinresearch)
- Gendered Innovations, Stanford University: [http://genderedinnovations.stanford.edu/methods-sex-and-gender-analysis.html](http://genderedinnovations.stanford.edu/methods-sex-and-gender-analysis.html)
- Canadian Institutes of Health Research: [https://www.cihr-irsc-igh-isfh.ca/](https://www.cihr-irsc-igh-isfh.ca/)

# LS25 / Guidelines for good scientific practice and ethics

#### <span lang="EN-GB" style="mso-ansi-language: EN-GB;">Good scientific practice</span>

<span lang="EN-GB" style="mso-ansi-language: EN-GB;">Compliance with the **rules for good scientific practice,** including the observance of ethical aspects in research, is mandatory. This pertains to the application process and, in case of funding, the research work. </span>

- <span lang="EN-GB" style="mso-ansi-language: EN-GB;">WWTF is member of the Austrian Agency for Research Integrity (OeAWI) and thus committed to their standards for good scientific practice. Hence, applicants must comply to [OeAWI standards](https://oeawi.at/en/guidelines/) </span>
- <span lang="EN-GB" style="mso-ansi-language: EN-GB;">In case of suspected scientific misconduct, WWTF will employ the ombudsperson at the applicant’s institution or request OeAWI to investigate the case.</span>
- <span lang="EN-GB" style="mso-ansi-language: EN-GB;">Based on the outcome of investigations by the ombudsperson or OeAWI, WWTF reserves the right to exclude the applicants and the application from the involved and future calls. </span>

#### <span lang="EN-GB" style="mso-ansi-language: EN-GB;">Ethical aspects</span>

<span lang="EN-GB" style="mso-ansi-language: EN-GB;">Project proposals may include **ethical aspects** that require the approval from an ethics committee/institutional review board. Please consider WWTF’s requirements regarding ethical aspects at the different stages of the call and, if applicable, upon the selection of a project for funding.</span>

- <span lang="EN-GB" style="mso-ansi-language: EN-GB;">In the short proposal, applicants provide a brief statement regarding the ethical aspects of the project. Applicants must indicate whether a formal ethical approval is required for the proposed work.</span>
- <span lang="EN-GB" style="mso-ansi-language: EN-GB;">Upon invitation to submit a full proposal, applicants must provide a more detailed description of the ethical aspects of the proposed work. If available, the ethical approval (final or preliminary) or confirmation of submission of an ethical approval should be submitted. If an ethical approval for the proposed work has yet not been granted, applicants must provide a timeline and an explanation of the feasibility of obtaining the necessary ethical approvals. In the latter case, applicants commit themselves to obtaining the required permits to commence the project in a timely manner, should it be selected for funding.</span>
- <span lang="EN-GB" style="mso-ansi-language: EN-GB;">Upon selection for funding, submission of the final ethical approvals to WWTF is a prerequisite for the funding contract. As projects must start no later than 6 months after funding approval, grantees must ensure that ethical approvals are submitted to WWTF in time for the funding contract to be concluded.</span>

<p class="callout warning"><span lang="EN-GB" style="mso-ansi-language: EN-GB;">Please note that the feasibility of obtaining the required ethical approval will be considered during the evaluation of the full proposal. Insufficient demonstration of the ability to obtain ethical approvals within a timely manner may result in the project being excluded by the jury panel.</span></p>

Please note the following requirements regarding **ethical approvals** for WWTF-funded projects.

- <span lang="EN-GB" style="mso-ansi-language: EN-GB;">The approval by the ethics committee should be specific for the planned WWTF project. Therefore, the title of the project should be the same as on the approval (minor deviations are possible). If the title of the approved research differs significantly from the proposed project, a statement must be provided (in the Funding Portal), confirming that the approval will cover the planned research.</span>
- <span lang="EN-GB" style="mso-ansi-language: EN-GB;">If the main applicant for the ethical approval is not a core team member (i.e., PI&amp;C or co-PI) of the WWTF proposal, a clear statement must be included in the proposal, in which a core team member confirms that he/she is authorized to conduct the planned research within this ethical approval. </span>
- <span lang="EN-GB" style="mso-ansi-language: EN-GB;">If the planned research is covered by an existing approval, the applicants must submit the extension of the approval (“Verlängerung der Gültigkeit des Votums”). The above also applies for extensions.</span>

<p class="callout warning"><span lang="EN-GB" style="mso-ansi-language: EN-GB; mso-bidi-font-weight: bold;">Non-compliance will result in the rejection of the proposal on formal grounds.</span></p>

<div id="bkmrk-" style="mso-element: footnote-list;"><div id="bkmrk--1" style="mso-element: footnote;"></div></div>

# LS25 / Open Science

<span lang="EN-US">WWTF requires compliance with its </span><span lang="DE">[<span lang="EN-US">Open Science Policy</span>](https://wwtf.at/upload/wwtf_open-science-policy_09032022.pdf)</span><span lang="EN-US">. This document outlines the rights, roles and responsibilities of WWTF, researchers, and research organizations.</span>

# LS25 / Use of generative AI in the application process

WWTF recognizes that the use of genAI tools is pervasive and can facilitate proposal writing, for example in relation to improving written language. However, substantial use of genAI must be declared as such for the sake of transparency.

<p class="callout info">“Substantial use” is defined in line with the European Commission’s definition: “\[…\] using generative AI as a basic author support tool is not a substantial use. However, interpreting data analysis, carrying out a literature review, identifying research gaps, formulating research aims, developing hypotheses, etc. could have a substantial impact.” (EC 2024: Living Guidelines on the responsible use of generative AI in research.) </p>

This mainly concerns critical parts of scientific relevance, such as hypothesis formulation and the scientific project plan. Applicants will be required to provide statements on the use of generative AIs at both the short and full proposal stages. WWTF emphasizes the importance of human responsibility for the content submitted at all stages of the application process.

<p class="callout info">WWTF does not allow the use of genAI in the evaluation process.</p>

# LS25 / Selection and decision process

<span lang="EN-GB" style="mso-ansi-language: EN-GB;">Applications must be submitted via the online Funding Portal in the specified timeframes. Submissions after the deadline will not be considered. </span>

<span lang="EN-GB" style="mso-ansi-language: EN-GB;">The core element of WWTF’s decision-making processes is an **international jury** mandated to make a funding recommendation to the WWTF boards. </span>

- <span lang="EN-GB">Depending on the call (size, scope etc) the jury is comprised of 6-12 outstanding international experts who have no current affiliation to an Austrian institution.</span>
- Jury members are selected by WWTF according to their expertise in the call topic. They have no known conflict of interest prior to the submission deadline. For details, see section on evaluation below.
- The names of jury members will be published on the WWTF website after the WWTF Board of Directors finalize the formal funding decision.

#### <span lang="EN-US">Formal eligibility check by WWTF</span>

<span lang="EN-GB" style="mso-ansi-language: EN-GB;">WWTF office will conduct a formal eligibility check of the proposal based on the criteria outlined in the </span><span lang="DE">[<span lang="EN-GB" style="color: #008fd4; mso-themecolor: accent1; mso-ansi-language: EN-GB;">WWTF Funding Guideline</span>](https://wwtf.at/upload/wwtf_forderrichtlinie_08112021_final(1).pdf)</span><span lang="EN-GB" style="color: #008fd4; mso-themecolor: accent1; mso-ansi-language: EN-GB;">, </span><span lang="EN-GB" style="mso-ansi-language: EN-GB;">and this document. This includes:</span>

- <span lang="EN-GB" style="mso-ansi-language: EN-GB;">All required signatures from the appropriate persons are uploaded.</span>
- <span lang="EN-GB" style="mso-ansi-language: EN-GB;">All projects will be checked for plagiarism with software.</span>
- <span lang="EN-GB" style="mso-ansi-language: EN-GB;">Submission of the same or highly similar research ideas to other funding organizations, which must be explicitly declared in the full proposal. Application for funding at other organizations is permitted and will not impact the evaluation. In case of funding, applicants will be asked by which organization they wish to be funded, as double funding is not permitted by WWTF.</span>

<span lang="EN-GB" style="mso-ansi-language: EN-GB; mso-bidi-font-weight: bold;">Substantial deficiencies and missing sections in the application will lead to the exclusion of the application from further evaluation and rejection on formal grounds. The strict timeline of the call does not allow for proposals to be sent back to the applicants for amendments.</span>

#### Evaluation of short proposals

- <span lang="EN-GB" style="mso-ansi-language: EN-GB; mso-bidi-font-weight: bold;">Each proposal is independently assessed by at least two jury members based on the evaluation criteria. </span>
- <span lang="EN-GB" style="mso-ansi-language: EN-GB; mso-bidi-font-weight: bold;">The jury decides in a meeting (on-site or online) if a short proposal should be invited to the full proposal stage. This usually takes place 1-2 months after the short proposal submission deadline.<span style="mso-spacerun: yes;"> </span></span>
- <span lang="EN-GB" style="mso-ansi-language: EN-GB;">All applicants will be promptly informed about the decision. Unsuccessful applicants will be provided with a short jury statement explaining the decision. Successful applicants will be informed that they are invited to submit a full-length proposal. </span>

#### Evaluation of full proposals

- <span lang="EN-GB" style="mso-ansi-language: EN-GB;">All duly submitted full proposals are checked again for formal aspects. Proposals which do not meet the formal requirements will be rejected at this stage. </span>
- <span lang="EN-GB" style="mso-ansi-language: EN-GB;">The information provided in the full proposal must be consistent with the short proposal and extend it by providing more information and details. Major deviations to the short proposal must be justified explicitly. If major deviations cannot be satisfactorily explained, it may be rejected by the jury at this stage.<span style="mso-spacerun: yes;"> </span></span>

<span lang="EN-GB" style="mso-ansi-language: EN-GB;">Eligible full proposals will undergo a **review process**.<span style="mso-spacerun: yes;"> </span></span>

- <span lang="EN-GB" style="mso-ansi-language: EN-GB;">WWTF will obtain a minimum of two (usually 3-4) written reviews for each proposal.</span>
- <span lang="EN-GB" style="mso-ansi-language: EN-GB;">Reviewers are international experts in the topic(s) of the proposals. WWTF does not contact reviewers based in Austria. WWTF aims for diversity in the cohort of reviewers for a call (gender, age, countries). </span>
- <span lang="EN-GB" style="mso-ansi-language: EN-GB;">All reviewers will be checked by the WWTF office for potential conflicts of interests with the applicants. As a rule, reviewers should not have close professional relations to any of the applicants in the project team. Practically, this excludes reviewers that have published with the applicants within the last five years or have had a collaboration in a research project in this timeframe. In case of very close cooperation with the applicant(s) over a longer period of time, the reviewer will also be excluded. Joint publications in an edited volumes/proceeding, “community papers” with more than 30 authors or common attendances in workshops and conferences do not qualify as conflict of interest. Additionally, reviewers are asked to disclose any potential conflict of interest. </span>
- <span lang="EN-GB" style="mso-ansi-language: EN-GB; mso-bidi-font-weight: bold;">Reviewers will be asked to provide their assessment of the proposal through a standardised online questionnaire.</span>
- <span lang="EN-GB" style="mso-ansi-language: EN-GB; mso-bidi-font-weight: bold;">The expert reviewers remain anonymous to the applicants. </span>
- <span lang="EN-GB" style="mso-ansi-language: EN-GB;">Jury members nominate reviewers. In addition, in the full proposal submissions, applicants are asked to suggest <span style="color: black; mso-themecolor: text1;">5 </span>experts whom they deem qualified to review the proposal. WWTF office will check the reviewers for potential conflict of interests. WWTF office is free to choose/not to choose any of the suggested experts. </span>
- <span lang="EN-GB" style="mso-ansi-language: EN-GB; mso-bidi-font-weight: bold;">Applicants may also exclude up to<span style="color: #c45911;"> </span><span style="color: black; mso-themecolor: text1;">3 </span>persons without stating any reasons. Reviewers on the negative list will not be contacted.<span style="mso-spacerun: yes;"> </span></span>

<span lang="EN-GB" style="mso-ansi-language: EN-GB;">Applicants will have the opportunity to **respond** in writing to the external reviews.</span>

- <span lang="EN-GB" style="mso-ansi-language: EN-GB; mso-bidi-font-weight: bold;">The purpose of the applicant response step is to allow correction of any factual errors or conceptual misunderstandings in the external reviews.</span>
- <span lang="EN-GB" style="mso-ansi-language: EN-GB;">The length of the applicant response will be limited to the equivalent of one A4 page of text. The response must be entered as text in the Funding Portal. <span style="mso-bidi-font-weight: bold;">Pictures, graphs, or other documents cannot be inserted or attached.</span></span>
- <span lang="EN-GB" style="mso-ansi-language: EN-GB;">Applicants will be given 7 calendar days to view and respond to the peer reviews. While the exact dates for the applicant response step are not fixed, an [indicative time period](https://wiki.wwtf.at/books/archiviert-life-sciences-call-2025-precision-medicine/page/ls25-structure-of-the-call "LS25 / Struture of the Call") is provided.</span>
- <span lang="EN-GB" style="mso-ansi-language: EN-GB;">All core team members will receive an email notification when the applicant response step is open in the Funding Portal. </span>
- <span lang="EN-GB" style="mso-ansi-language: EN-GB;">Submission of a response to reviews is not compulsory. However, the jury panel will be informed that all teams were provided with the opportunity to respond to reviews.</span>
- <span lang="EN-GB" style="mso-ansi-language: EN-GB;">More details about the scope and process of the applicant response phase will be available to core teams invited to submit a full proposal.</span>

#### <span lang="EN-US">Full Proposal Jury meeting</span>

The jury will convene about 3-4 months after the submission deadline of the full proposals to select full proposals to recommend for funding. The jury may be extended by additional members in case supplementary expertise is needed to cover the topics of the proposals. At least two jury members are assigned to each proposal and act as rapporteurs for the proposals.

- The basis for the evaluation by the jury are the full proposals, the external reviews, and the applicant’s response to reviews. The arguments brought forward in the review reports will be carefully balanced with the jury’s own expertise.
- The result is a recommendation for each project: “to be funded” or “not to be funded”.

#### <span lang="EN-US">Formal funding decision</span>

<span lang="EN-GB" style="mso-ansi-language: EN-GB;">The jury recommendation will be formally confirmed first by the WWTF Advisory Board and then approved by the WWTF Board of Directors. </span>

- <span style="mso-bookmark: _Toc85638314;"><span style="mso-bookmark: _Toc85631473;"><span lang="EN-GB" style="mso-ansi-language: EN-GB;">Applicants will be promptly informed about the decision.</span></span></span>
- <span style="mso-bookmark: _Toc85638314;"><span style="mso-bookmark: _Toc85631473;"><span lang="EN-GB" style="mso-ansi-language: EN-GB;">The decision may include budget cuts as well as additional conditions and recommendations. </span></span></span>
- <span style="mso-bookmark: _Toc85638314;"><span style="mso-bookmark: _Toc85631473;"><span lang="EN-GB" style="mso-ansi-language: EN-GB;">Unsuccessful applicants will receive a short statement by the jury explaining the main reasons why the project was not selected for funding.</span></span></span>

<p class="callout info"><span style="mso-bookmark: _Toc85638314;"><span style="mso-bookmark: _Toc85631473;"><span lang="EN-GB" style="mso-ansi-language: EN-GB;">Please note that WWTF does not allow the opportunity for rebuttals to either recommendations by the jury panel or decisions by the WWTF Board of Directors.</span></span></span></p>

# LS25 / Funding contract

<span lang="EN-GB" style="mso-ansi-language: EN-GB; mso-bidi-font-weight: bold;">In case of funding, WWTF office will contact the PI&amp;C to draw up the funding contract. </span>

- <span lang="EN-GB" style="mso-ansi-language: EN-GB;">WWTF encourages projects to start as soon as possible after the formal funding decision by the WWTF Board of Directors. To facilitate a timely project start, WWTF will directly contact the PI&amp;C shortly after the funding decision to commence the contracting process.</span>
- <span lang="EN-GB" style="mso-ansi-language: EN-GB;">The formal start of the project may be **no later than 6 months** after the formal funding decision. Please note that WWTF does not require all team members of the funded project to begin by the project’s start date. However, WWTF expects grantees to nominate a formal starting date for their project that is no later than 6 months after the notification of the funding decision.</span>
- <span lang="EN-GB" style="mso-ansi-language: EN-GB;">The PI&amp;C will be provided with the necessary documents for the contracts.</span>
- The <span lang="EN-GB">formal funding contract will be signed between WWTF and the host institution of the PI&amp;C. In Joint Projects, the host institution of the co-PI in Lower Austria is an additional contract partner.</span>
- For universities, this is a project according to §27 of the Universities Act 2002. The institution then authorizes the respective PI to sign for the full scientific and financial responsibility of the project.

# LS25 / Monitoring and reporting

<span lang="EN-GB" style="mso-ansi-language: EN-GB;">Funded teams commit themselves to delivering reports and participating in evaluation and monitoring. WWTF offers the possibility to adapt the work plan according to project needs. For details, see the</span><span lang="DE"> [Reporting and Accounting Guideline](https://wwtf.at/upload/anhang_berichtswesen-und-abrechnungsmodalitaten_17072024.pdf)</span><span lang="EN-GB" style="color: #008fd4; mso-themecolor: accent1; mso-ansi-language: EN-GB;">.</span>

# LS25 / Community Building

<span lang="EN-US" style="mso-ansi-language: EN-US;">WWTF is highly committed to supporting the growing ICT community in Vienna. To this end, several community building activities will be offered throughout the funding cycle. Funded teams will be invited to participate in these activities to foster collaborations between and beyond WWTF funded projects. </span>